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淡水双壳贝类背角无齿蚌的染色体水平基因组组装

Chromosome-level genome assembly of the freshwater bivalve Anodonta woodiana.

作者信息

Chen Xiubao, Jiang Tao, Xue Junren, Gu Mengying, Wang Meiyi, Liu Kai

机构信息

Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi, 214081, China.

Wuxi Fisheries College, Nanjing Agricultural University, Wuxi, 214081, China.

出版信息

Sci Data. 2025 May 2;12(1):731. doi: 10.1038/s41597-025-05078-6.

DOI:10.1038/s41597-025-05078-6
PMID:40316565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12048480/
Abstract

The freshwater bivalve Anodonta (Sinanodonta) woodiana originated in the Yangtze River basin of China and is now widely distributed in Asia, Europe, North America, and Africa. This species has important economic and ecological value. Using Illumina, PacBio, and Hi-C technology, a high-quality chromosome-level genome of A. woodiana was assembled. The genome size was 2.80 Gb, with a contig N50 of 4.01 Mb and a scaffold N50 of 143.34 Mb. In total, 1609 contigs, accounting for 99.57% of the total assembled genome, were anchored into 19 chromosomes. In total, 1.51 Gb repeat sequences were annotated and 44,785 protein-coding genes were predicted. This study is the first to reveal the genome of A. woodiana and the genus Anodonta, which will effectively contribute to investigations of this species' biology, molecular mechanisms in response to environmental stress, and resource management.

摘要

淡水双壳贝类背角无齿蚌(中华无齿蚌)原产于中国长江流域,现广泛分布于亚洲、欧洲、北美洲和非洲。该物种具有重要的经济和生态价值。利用Illumina、PacBio和Hi-C技术,组装了高质量的背角无齿蚌染色体水平基因组。基因组大小为2.80Gb,重叠群N50为4.01Mb,支架N50为143.34Mb。总共1609个重叠群(占总组装基因组的99.57%)被锚定到19条染色体上。总共注释了1.51Gb的重复序列,并预测了44785个蛋白质编码基因。本研究首次揭示了背角无齿蚌及无齿蚌属的基因组,这将有效地促进对该物种生物学、应对环境胁迫的分子机制及资源管理的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/42dc561ef883/41597_2025_5078_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/b34d0781425b/41597_2025_5078_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/dab8be310426/41597_2025_5078_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/a56f41867767/41597_2025_5078_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/42dc561ef883/41597_2025_5078_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/b34d0781425b/41597_2025_5078_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/dab8be310426/41597_2025_5078_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/a56f41867767/41597_2025_5078_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f64/12048480/42dc561ef883/41597_2025_5078_Fig4_HTML.jpg

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