Onal Yilmaz, Günkan Ahmet, Ercan Volga Ulas, Bocanegra-Becerra Jhon E, Ergul Umut, Ramazanoglu Leyla, Cicek Esin Derin, Kahraman Ahmet Nedim, Velioglu Murat
Department of Radiology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Radiológica, Unidade General Osório, Nova Friburgo, Rio de Janeiro, Brazil.
Neurosurg Rev. 2025 May 3;48(1):401. doi: 10.1007/s10143-025-03554-6.
The aim of this study was to reveal our preliminary experience related to the technical success and safety of the Titan aspiration catheter in acute ischemic stroke (AIS) patients.
Forty-eight consecutive AIS patients (mean age 62.6 ± 13.8 years) treated with Titan aspiration catheter, using both the ADAPT technique or combined approach with a stent retriever, were included in the study. The primary outcome was successful recanalization (mTICI ≥ 2c-3), and the secondary outcomes were complication rates and 90th day clinical outcomes.
The mean NIHSS score of the patients was 14.63 ± 3.04, and the mean time from groin puncture to recanalization was 24.72 ± 12.48 min. Successful recanalization was achieved in 35 (72.91%) patients. Postprocedural symptomatic hemorrhage was seen in 5 patients (10.41%). Rate of good clinical outcomes on day 90 was 45.83%. There were 7 deaths (14.58%) in this study.
The aspiration thrombectomy method is increasingly being used in AIS cases due to its rapid patency rate and its relatively easy application. Because of technological advances, newer aspiration catheters have been improved and are commercially available. Our preliminary results showed that the Titan aspiration catheter could be a useful tool both with the ADAPT technique and the combined approach. Additionally, the fact that the device is offered as a kit may be important in terms of cost-effectiveness.
本研究旨在揭示我们在急性缺血性卒中（AIS）患者中使用Titan抽吸导管的技术成功率和安全性方面的初步经验。
本研究纳入了48例连续的AIS患者（平均年龄62.6±13.8岁），这些患者使用Titan抽吸导管，采用ADAPT技术或与支架取栓器联合使用的方法进行治疗。主要结局是成功再通（mTICI≥2c-3），次要结局是并发症发生率和第90天的临床结局。
患者的平均美国国立卫生研究院卒中量表（NIHSS）评分为14.63±3.04，从腹股沟穿刺到再通的平均时间为24.72±12.48分钟。35例（72.91%）患者实现了成功再通。术后有5例患者（10.41%）出现症状性出血。第90天良好临床结局的发生率为45.83%。本研究中有7例死亡（14.58%）。
由于抽吸血栓切除术的再通速度快且应用相对简便，该方法在AIS病例中的应用越来越广泛。随着技术进步，新型抽吸导管已得到改进并可在市场上买到。我们的初步结果表明，Titan抽吸导管在ADAPT技术和联合使用方法中都可能是一种有用的工具。此外，该设备以套件形式提供这一事实在成本效益方面可能很重要。
