Khan Abid Hasan, Bhuiyan Md Saruar Hossain, Kabir Md Feroz, Hossain Md Zahid, Jahan Sharmila, Hossain K M Amran, Rahman Ehsanur
Department of Physiotherapy and Rehabilitation, Jashore University of Science and Technology (JUST), Jashore, 7408, Bangladesh.
Trials. 2025 May 3;26(1):146. doi: 10.1186/s13063-025-08848-0.
Adhesive capsulitis (AC) is a progressive inflammatory condition of the shoulder that causes functional limitations and leads to long-term disability. The study aimed to elicit the effectiveness of proprioceptive neuromuscular facilitation (PNF) compared to standard physiotherapy approaches on AC.
An assessor-blinded single-centre randomised control trial (RCT) was carried out on 80 AC patients between May 2022 and December 2023 in Bangladesh. Random assigned and concealed allocated patients were recruited equally (n = 40) to each PNF and conventional capsular stretching group. The experimental group received a PNF approach, and the control group received capsular stretching to the affected shoulder for 24 sessions in 6 weeks. Both groups received electrical modalities as standard treatment. The primary outcome was pain measured by the numeric pain rating scale (NPRS) and range of motion in a universal goniometer. The secondary outcome was functional limitation measured by the shoulder pain and disability index (SPADI). As per the distribution of data, non-parametric tests were employed to analyse the superiority between and within groups with intention-to-treat analysis.
Baseline compatibility was noted in all the key variables (p > 0.05). Both PNF and capsular stretching had a decrease in pain compared to baseline in all capsular pattern positions (p < 0.001), and PNF had more significant improvement compared to control (p < 0.001). Both groups had equal improvement in shoulder ROM (p < 0.001) except abduction (p < 0.05). Both groups had improvements in disability (p < 0.05), and PNF had statistical superiority of improvement (p < 0.001).
The findings of this study support the potential of PNF intervention for 6 weeks as a treatment for shoulder adhesive capsulitis, showing improvements in pain, ROM and functional disability. However, further multicentre trials with a follow-up design are needed to fully understand the superiority of PNF on shoulder AC, encouraging continued engagement in this area of research.
The Australian New Zealand Clinical Trial Registry (ACTRN12621001299897). Registered on 27 September 2021, prospectively registered.
粘连性肩关节囊炎(AC)是一种肩部进行性炎症性疾病,会导致功能受限并导致长期残疾。本研究旨在探讨与标准物理治疗方法相比,本体感觉神经肌肉促进法(PNF)对粘连性肩关节囊炎的疗效。
2022年5月至2023年12月期间,在孟加拉国对80例粘连性肩关节囊炎患者进行了一项评估者盲法单中心随机对照试验(RCT)。将随机分配和隐藏分配的患者平均分为两组(n = 40),分别进入PNF组和传统关节囊拉伸组。实验组采用PNF方法,对照组对患侧肩部进行关节囊拉伸,共24次,为期6周。两组均接受电疗法作为标准治疗。主要结局指标是用数字疼痛评分量表(NPRS)测量的疼痛和用通用角度计测量的活动范围。次要结局指标是用肩部疼痛和残疾指数(SPADI)测量的功能受限情况。根据数据分布情况,采用非参数检验对组间和组内的优越性进行意向性分析。
所有关键变量在基线时均具有可比性(p > 0.05)。与基线相比,PNF组和关节囊拉伸组在所有关节囊模式位置的疼痛均有所减轻(p < 0.001),且PNF组与对照组相比改善更显著(p < 0.001)。除外展外(p < 0.05),两组在肩部活动度方面的改善程度相同(p < 0.001)。两组在残疾情况方面均有改善(p < 0.05),且PNF组在改善方面具有统计学优势(p < 0.001)。
本研究结果支持PNF干预6周作为治疗粘连性肩关节囊炎的潜力,在疼痛、活动度和功能残疾方面均有改善。然而,需要进一步进行多中心随访试验,以充分了解PNF在粘连性肩关节囊炎治疗中的优越性,鼓励在该研究领域持续开展研究。
澳大利亚新西兰临床试验注册中心(ACTRN12621001299897)。于2021年9月27日注册,前瞻性注册。