Zhao Hanghang, Xu Xing, Cui Wenquan, Geng Longlong, Peng Xiaoming, Yang Jingren, Shao Xianzhao, Liu Yanbiao
School of Chemical and Environment Science, Shaanxi University of Technology, Hanzhong, Shaanxi, 723001, P. R. China.
Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Qingdao, 266237, P. R. China.
Adv Mater. 2025 Jul;37(30):e2503217. doi: 10.1002/adma.202503217. Epub 2025 May 2.
Single-atom catalysts (SACs) have garnered significant attention in the applications of environmental remediation based on Fenton-like systems. Current research on Fenton-like single-atom catalysis often emphasizes catalytic activity and mechanism regulation, while paying limited attention to the simultaneous enhancement of both activity and stability-a critical factor for the practical and scale-up applications of SACs. This review systematically summarizes recent advances in synchronization strategies for improving the activity and stability of Fenton-like single-atom catalysis, with a focus on the design principles and mechanisms of four key strategies: coordination engineering, confinement effects, carrier substitution, and catalytic module design. To the best of knowledge, this represents the first comprehensive review of Fenton-like single-atom catalysis from the perspective of concurrent optimization of activity and stability. Additionally, the auxiliary role of machine learning and lifecycle assessment (LCA) is evaluated in advancing these synchronization strategies. By investigating the interplay among different support materials, coordination configurations, and reaction environments, as well as enlarged modules, key factors governing the stability/activity of SACs are highlighted, and future directions are proposed for developing next-generation catalysts with high efficiency and long-term durability for practical environmental remediation.
单原子催化剂（SACs）在基于类芬顿体系的环境修复应用中受到了广泛关注。目前关于类芬顿单原子催化的研究通常侧重于催化活性和机理调控，而对同时提高活性和稳定性的关注有限，而这是SACs实际应用和扩大规模的关键因素。本文综述系统总结了提高类芬顿单原子催化活性和稳定性同步策略的最新进展，重点介绍了四种关键策略的设计原则和机理：配位工程、限域效应、载体替代和催化模块设计。据我们所知，这是首次从活性和稳定性同步优化的角度对类芬顿单原子催化进行全面综述。此外，还评估了机器学习和生命周期评估（LCA）在推进这些同步策略中的辅助作用。通过研究不同载体材料、配位构型和反应环境以及扩大模块之间的相互作用，突出了影响SACs稳定性/活性的关键因素，并为开发用于实际环境修复的高效、长期耐用的下一代催化剂提出了未来方向。
