Gavett Brandon E, Tomaszewski Farias Sarah, Tiet Quyen Q, Park Van T, Harvey Danielle, Vuong Quyen, Hinton Ladson, Kanaya Alka M, Whitmer Rachel A, Mai Lauren, Meyer Oanh L
Department of Neurology, University of California Davis School of Medicine, Sacramento, California, USA.
Clinical Psychology PhD Program, California School of Professional Psychology at Alliant International University, Emeryville, California, USA.
Alzheimers Dement. 2025 May;21(5):e70097. doi: 10.1002/alz.70097.
Vietnamese Americans represent an understudied population with unique risk factors relevant to cognitive aging. The current study sought to model global cognition in the Vietnamese Insights into Cognitive Aging Program (VIP) study and harmonize ability estimates with the National Alzheimer's Coordinating Center (NACC) Uniform Data Set.
Cognitive data from VIP (N = 548) and NACC (N = 15,923) were analyzed using item response theory. Seven common items were assessed for differential item functioning (DIF); items without salient DIF were used to harmonize the cognitive composite score across the two cohorts.
Although five of the seven common items showed evidence of DIF, the magnitude of this DIF was negligible, affecting the factor score estimates of only 12 (2.19%) VIP participants by more than one standard error.
Global cognitive functioning can be estimated in Vietnamese American immigrants with minimal bias and psychometrically matched to one of the largest studies of cognitive aging and dementia worldwide.
This is the first known study to model cognition in older Vietnamese Americans. Global cognition was harmonized with minimal bias across two diverse cohorts. Differential item functioning was found in five of seven items, but the impact was not salient. Results create new opportunities to study health disparities in an underrepresented group.
美籍越南人是一个研究较少的群体，具有与认知老化相关的独特风险因素。当前的研究旨在对越南认知老化洞察项目（VIP）中的整体认知进行建模，并使能力估计值与国家阿尔茨海默病协调中心（NACC）统一数据集保持一致。
使用项目反应理论对VIP（N = 548）和NACC（N = 15,923）的认知数据进行分析。对七个共同项目进行差异项目功能（DIF）评估；没有显著DIF的项目用于协调两个队列的认知综合得分。
虽然七个共同项目中的五个显示出DIF的证据，但这种DIF的程度可以忽略不计，仅影响12名（2.19%）VIP参与者的因子得分估计值超过一个标准差。
可以以最小的偏差估计美籍越南移民的整体认知功能，并在心理测量学上与全球最大的认知老化和痴呆研究之一相匹配。
这是第一项对老年美籍越南人的认知进行建模的已知研究。在两个不同的队列中以最小的偏差协调了整体认知。七个项目中的五个发现了差异项目功能，但影响并不显著。研究结果为研究一个代表性不足群体中的健康差异创造了新机会。
