一种用于无线心脏起搏的基于聚对二甲苯的微机电系统血管内植入物。
A PARYLENE-BASED MEMS INTRAVASCULAR IMPLANT FOR WIRELESS CARDIAC PACING.
作者信息
Shang Kuang-Ming, Hsiai Tzung, Tai Yu-Chong
机构信息
Department of Medical and Electrical Engineering, Caltech, Pasadena, CA, USA.
Department of Bioengineering, UCLA, Los Angeles, CA, USA.
出版信息
Proc IEEE Int Conf Micro Electro Mech Syst. 2024 Jan;2024:437-440. doi: 10.1109/mems58180.2024.10439358. Epub 2024 Feb 22.
We present a MEMS intravascular implant designed for wireless cardiac pacing. This micropacer implant is meticulously engineered to refine the fabrication process, provide adequate cardiac stimulation, and maintain a compact form factor. An innovative roll-to-capsule technique allows a one-piece micropacer, which includes a parylene circuit board for discrete components, stimulating ring electrodes, and an encapsulation layer. Our design employs a low-frequency inductive power transfer using primary and secondary coils in a back-to-back configuration, ensuring consistent power delivery for pacing even if the coils become minutely misaligned. The finalized device measures 1.8 mm in diameter and 12 mm in length, allowing for catheter-delivered insertion into the cardiac vein. Benchtop tests confirmed the device's capability to deliver a 3.5V DC output voltage with a coil separation of one inch.
我们展示了一种专为无线心脏起搏设计的微机电系统（MEMS）血管内植入物。这种微型起搏器植入物经过精心设计，以优化制造工艺，提供足够的心脏刺激，并保持紧凑的外形尺寸。一种创新的卷对胶囊技术实现了一体式微型起搏器，其包括用于分立元件的聚对二甲苯电路板、刺激环形电极和封装层。我们的设计采用了背靠背配置的初级和次级线圈进行低频感应功率传输，即使线圈出现微小的错位，也能确保为起搏提供稳定的功率传输。最终的装置直径为1.8毫米，长度为12毫米，可通过导管插入心脏静脉。台式测试证实了该装置在线圈间距为一英寸时能够提供3.5V直流输出电压的能力。
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