Lu Xinyuan, Wang Jiwei, Chen Sikun, Lv Lin, Yu Jinming
Key Laboratory of Public Health Safety Ministry of Education, National Health Commission Key Laboratory of Health Technology Assessment, School of Public Health, Fudan University, Shanghai 200043, China.
Int J Hypertens. 2025 Apr 26;2025:9954099. doi: 10.1155/ijhy/9954099. eCollection 2025.
Hypertension remains a major public health challenge globally, with suboptimal adherence to treatment and lifestyle modifications exacerbating cardiovascular risks. This study evaluates multidimensional adherence (medication, diet, and behavior) and its determinants among hypertensive patients in rural Northeast China. A cross-sectional study enrolled 6352 adults aged ≥ 40 years with diagnosed and poorly controlled hypertension from rural villages across five cities (Benxi, Chaoyang, Dandong, Donggang, and Fuxin) in Liaoning Province, Northeast China, using multistage cluster sampling. Adherence was assessed via standardized questionnaires, with logistic regression analyzing sociodemographic, clinical, and behavioral predictors. Medication adherence was reported by 73.7% of participants, while dietary and behavioral adherence rates were 10.5% and 29.3%, respectively. Ethnic disparities emerged, with Han Chinese exhibiting lower medication adherence (aOR = 0.485, 95% CI: 0.377-0.624). Cohabiting with children enhanced dietary adherence (aOR = 2.184, 95% CI: 1.854-2.573), whereas widowed status reduced both dietary (aOR = 0.698, 95% CI: 0.528-0.924) and behavioral adherence (aOR = 0.726, 95% CI: 0.595-0.887). Higher hypertension knowledge scores positively influenced all adherence domains ( < 0.05). Adherence among rural hypertensive patients is multidimensional, shaped by cultural, socioeconomic, and behavioral factors. Targeted interventions addressing dietary sodium reduction, family-based support, and health literacy improvement are urgently needed. This study underscores the importance of integrating region-specific strategies into hypertension management programs to mitigate cardiovascular morbidity in high-risk populations.
高血压仍然是全球主要的公共卫生挑战,治疗依从性欠佳以及生活方式改变不足加剧了心血管疾病风险。本研究评估了中国东北农村地区高血压患者的多维度依从性(药物治疗、饮食和行为)及其决定因素。一项横断面研究采用多阶段整群抽样方法,纳入了中国东北辽宁省五个城市(本溪、朝阳、丹东、东港和阜新)农村地区6352名年龄≥40岁、已确诊且血压控制不佳的成年人。通过标准化问卷评估依从性,并采用逻辑回归分析社会人口统计学、临床和行为预测因素。73.7%的参与者报告了药物治疗依从性,而饮食和行为依从率分别为10.5%和29.3%。出现了种族差异,汉族的药物治疗依从性较低(调整优势比[aOR]=0.485,95%置信区间[CI]:0.377-0.624)。与子女同住可提高饮食依从性(aOR=2.184,95%CI:1.854-2.573),而丧偶状态则会降低饮食依从性(aOR=0.698,95%CI:0.528-0.924)和行为依从性(aOR=0.726,95%CI:0.595-0.887)。较高的高血压知识得分对所有依从性领域均有积极影响(P<0.05)。农村高血压患者的依从性具有多维度特点,受文化、社会经济和行为因素影响。迫切需要针对减少饮食中的钠摄入、基于家庭的支持以及提高健康素养进行有针对性的干预措施。本研究强调了将区域特定策略纳入高血压管理项目以降低高危人群心血管疾病发病率的重要性。
J Geriatr Cardiol. 2025-1-28
Lancet Reg Health West Pac. 2023-6-20
Cost Eff Resour Alloc. 2023-8-30
Int J Environ Res Public Health. 2022-6-26