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一名因胶原蛋白VI相关型肌营养不良导致身材极度矮小和体重过低的女性怀孕。

Pregnancy in a woman with extreme short stature and low body weight secondary to a collagen VI-related muscular dystrophy.

作者信息

O'Sullivan Joseph, Mahmood Hifsa, Curry Ruth A, Frise Charlotte

机构信息

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Imperial College Healthcare NHS Trust, London, UK.

出版信息

Obstet Med. 2025 Jun;18(2):123-126. doi: 10.1177/1753495X231219298. Epub 2023 Dec 21.

DOI:10.1177/1753495X231219298
PMID:40322673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12046188/
Abstract

Pregnancy poses significant physiological demands, and women of extreme short stature may be particularly at risk of complications. Described here are two pregnancies in a woman who was 130 cm tall with a body mass index of 12 kg/m and the maternal and neonatal outcomes. The challenges encountered in the care of our patient included cardiorespiratory compromise, management of medication dosing, management of delivery and bleeding risk.

摘要

怀孕对生理有重大需求，身材极矮的女性可能尤其容易出现并发症。本文描述了一名身高130厘米、体重指数为12kg/m²的女性的两次怀孕情况以及母婴结局。在护理我们的患者过程中遇到的挑战包括心肺功能不全、药物剂量管理、分娩管理和出血风险。

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本文引用的文献

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Cureus. 2021 Dec 20;13(12):e20548. doi: 10.7759/cureus.20548. eCollection 2021 Dec.
2
Term spontaneous trial of labor in nulliparous women of short stature: A hospitals-based cohort study.身材矮小初产妇自然分娩试验：一项基于医院的队列研究。
Eur J Obstet Gynecol Reprod Biol. 2020 Mar;246:181-186. doi: 10.1016/j.ejogrb.2020.01.012. Epub 2020 Jan 14.
3
Adult height and risk of 50 diseases: a combined epidemiological and genetic analysis.成人身高与 50 种疾病风险：一项结合了流行病学和遗传学的分析。
BMC Med. 2018 Oct 25;16(1):187. doi: 10.1186/s12916-018-1175-7.
4
Birth risks according to maternal height and weight - an analysis of the German Perinatal Survey.根据母亲身高和体重得出的出生风险——德国围产期调查分析
J Perinat Med. 2018 Dec 19;47(1):50-60. doi: 10.1515/jpm-2017-0038.
5
Is growth hormone administration essential for in vitro fertilization treatment of female patients with growth hormone deficiency?生长激素替代治疗对生长激素缺乏的女性患者体外受精是否必不可少？
Syst Biol Reprod Med. 2019 Feb;65(1):71-74. doi: 10.1080/19396368.2018.1492044. Epub 2018 Jul 5.
6
Successful obstetric and anaesthetic management of a pregnant woman with achondroplasia.对一名患软骨发育不全的孕妇进行成功的产科和麻醉管理。
BMJ Case Rep. 2017 Oct 25;2017:bcr-2017-221238. doi: 10.1136/bcr-2017-221238.
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Eur J Clin Pharmacol. 2018 Feb;74(2):147-160. doi: 10.1007/s00228-017-2356-6. Epub 2017 Oct 24.
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