Zhai Lu, Gao Xiaoling
Second College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
The Second Hospital of Shanxi Medical University, No. 382, Wuyi Road, Xinghualing District, Taiyuan, Shanxi Province, 030001, People's Republic of China.
Sleep Breath. 2025 May 5;29(2):176. doi: 10.1007/s11325-025-03350-y.
Epidemiological studies have revealed significant associations between obstructive sleep apnea (OSA) and thyroid disorders, but discrepancies and contradictory results remain in some studies. Given the limited research currently available on this topic, this article aims to review the relationship between OSA and thyroid diseases.
PubMed, Embase, Web of Science, and The Cochrane Library were searched for the most recent literature on the correlation, mechanism, and treatment of OSA with various thyroid disorders for the last 10 years up to December 5, 2024.
There is a bidirectional association between OSA and thyroid disease. On the one hand, OSA not only increases the incidence of thyroid disorders, but also aggravates the severity of thyroid disorders, thereby negatively affecting treatment outcomes and prognosis; on the other hand, certain thyroid disorders may in turn promote the development of OSA.
OSA is closely associated with the development of thyroid disease, but the specific mechanism is not clear. Effective treatments for thyroid disease combined with OSA need to be further investigated.
流行病学研究揭示了阻塞性睡眠呼吸暂停（OSA）与甲状腺疾病之间存在显著关联，但一些研究中仍存在差异和相互矛盾的结果。鉴于目前关于该主题的研究有限，本文旨在综述OSA与甲状腺疾病之间的关系。
检索了PubMed、Embase、Web of Science和Cochrane图书馆，以获取截至2024年12月5日的过去10年中关于OSA与各种甲状腺疾病的相关性、机制和治疗的最新文献。
OSA与甲状腺疾病之间存在双向关联。一方面，OSA不仅增加甲状腺疾病的发病率，还会加重甲状腺疾病的严重程度，从而对治疗效果和预后产生负面影响；另一方面，某些甲状腺疾病可能反过来促进OSA的发展。
OSA与甲状腺疾病的发生密切相关，但具体机制尚不清楚。针对合并OSA的甲状腺疾病的有效治疗方法有待进一步研究。
