Demetriou Elpida, Economides Aliki, Fokou Maria, Lamnisos Demetris, Paschou Stavroula A, Papageorgis Panagiotis, Economides Panayiotis A
Eur Thyroid J. 2025 Jan 9;14(1). doi: 10.1530/ETJ-24-0176. Print 2025 Feb 1.
Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear.
To evaluate the impact of adiposity on thyroid nodules using body mass index (BMI), ultrasonographic (US) data and cytological data.
A retrospective cohort study of 310 patients with thyroid nodules was performed. Patients were categorized based on their BMI, and grayscale US data and fine-needle aspiration cytology results were evaluated.
Patients with BMI ≥ 25 kg/m2 were found to have a higher number of thyroid nodules compared to those with BMI < 25 kg/m2 (4.25 ± 2.42 vs 3.66 ± 1.93) (P value = 0.05). Patients with BMI ≥ 25 kg/m2 had more suspicious and malignant cytology than those with BMI < 25 kg/m2 (P value = 0.029). Patients with BMI ≥ 25 kg/m2 had more nodules with intermediate and high suspicion sonographic patterns. However, this did not reach statistical significance.
Overweight and obese patients have a trend for more thyroid nodules and have a higher risk of being diagnosed with thyroid malignancy.
肥胖可能与甲状腺结节有关。然而，其对结节数量和恶性风险的影响尚不清楚。
使用体重指数（BMI）、超声（US）数据和细胞学数据评估肥胖对甲状腺结节的影响。
对310例甲状腺结节患者进行回顾性队列研究。根据患者的BMI进行分类，并评估灰度超声数据和细针穿刺细胞学检查结果。
发现BMI≥25kg/m²的患者甲状腺结节数量高于BMI<25kg/m²的患者（4.25±2.42对3.66±1.93）（P值=0.05）。BMI≥25kg/m²的患者细胞学检查中可疑和恶性的情况比BMI<25kg/m²的患者更多（P值=0.029）。BMI≥25kg/m²的患者有更多具有中度和高度可疑超声特征的结节。然而，这未达到统计学意义。
超重和肥胖患者有甲状腺结节更多的趋势，且被诊断为甲状腺恶性肿瘤的风险更高。
