Hu Xiao, Liu Xiao-Dong, Gao Teng, Guo Qing
Department of Radiology, Tongling Municipal Hospital, Anhui Province, Tongling, China.
Medicine (Baltimore). 2025 May 2;104(18):e42374. doi: 10.1097/MD.0000000000042374.
This study aims to investigate the differential capabilities of high-resolution computed tomography (HRCT) and digital radiography (DR) in detecting small opacity characteristics and distribution patterns in pneumoconiosis, while evaluating HRCT's potential for early diagnosis of disease-associated complications. A retrospective evaluation was conducted on the HRCT and DR imaging findings of 206 dust-exposed workers. Quantitative CT assessment was carried out for emphysema and diffuse coniofibrosis. The density of mediastinal lymph nodes and the number of calcified lymph nodes were counted, and pleural plaques were graded. Moreover, the detection rates of small opacities and pneumoconiosis complications were compared between the 2 methods. Results demonstrated HRCT's superior capability to DR in detecting small opacities, characterizing their distribution patterns, and identifying complications. Significant positive correlations emerged between CT-based complication scores and pneumoconiosis staging. The findings indicate that HRCT enhances early detection of small opacities and enables quantitative assessment of comorbid pathologies, providing critical insights for timely clinical intervention and therapeutic management in early-stage pneumoconiosis patients.
本研究旨在探讨高分辨率计算机断层扫描(HRCT)和数字X线摄影(DR)在检测尘肺病中小阴影特征及分布模式方面的差异能力,同时评估HRCT对疾病相关并发症的早期诊断潜力。对206名接触粉尘工人的HRCT和DR影像结果进行回顾性评估。对肺气肿和弥漫性尘肺纤维化进行定量CT评估。计数纵隔淋巴结密度及钙化淋巴结数量,并对胸膜斑进行分级。此外,比较两种方法对小阴影和尘肺病并发症的检出率。结果表明,HRCT在检测小阴影、描述其分布模式及识别并发症方面比DR具有更强的能力。基于CT的并发症评分与尘肺病分期之间存在显著正相关。研究结果表明,HRCT可提高小阴影的早期检测率,并能对合并病症进行定量评估,为早期尘肺病患者的及时临床干预和治疗管理提供关键见解。