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国际注册机构中初次全髋关节置换术后翻修的累积风险:对选定的髋关节柄和髋臼杯进行系统评价和荟萃分析。

Cumulative risk of revision after primary total hip arthroplasty in registries internationally: systematic review and meta-analysis of selected hip stems and cups.

作者信息

Combescure Christophe, Smith James A, Barea Christophe, Hoogervorst Lotje A, Nelissen Rob, Marang-van de Mheen Perla J, Lübbeke Anne

出版信息

EFORT Open Rev. 2025 May 5;10(5):277-285. doi: 10.1530/EOR-2024-0020.

Abstract

PURPOSE

The objective was to investigate the consistency in cumulative revision rates (CRRs) for a selection of total hip arthroplasty cups and stems across national/regional hip arthroplasty registries worldwide.

METHODS

Ten cups and ten stems from total hip systems were randomly selected. Two frequently used implants across registries were added, totalling 11 cups and 11 stems. CRRs and 95% CIs were extracted from the latest annual registry reports using these implants. CRRs were pooled for each cup or stem, and differences between cup-stem combinations and between registries were investigated.

RESULTS

CRRs were available for ten cups and eight stems from eight registries, totalling 552,148 cups and 727,447 stems. Follow-up was 1-20 years. The 5-year CRR pooled for all cups was 2.9% (95% CI: 2.3-3.6) and for all stems, 3.0% (95% CI: 2.4-3.8). Homogeneous (consistent) CRRs with respect to both associated implant and country were observed for two cups and three stems. Significant differences in CRR were identified in one cup by associated implant only, in one cup by registry only, and in two cups and four stems for both. Sparse data prevented evaluation of four cups and one stem.

CONCLUSION

Registries' annual reports provide a large amount of publicly available information on CRRs of specific implants. These CRRs can be synthesised to improve the assessment of implant performance over time. Our CRR analysis represents a promising approach to detect implants with a consistent low- or high-risk pattern across registries.

摘要

目的

本研究旨在调查全球范围内国家/地区髋关节置换登记处中部分全髋关节置换髋臼杯和股骨柄的累积翻修率(CRR)的一致性。

方法

从全髋关节系统中随机选择10个髋臼杯和10个股骨柄。另外增加了两个在各登记处常用的植入物,共计11个髋臼杯和11个股骨柄。使用这些植入物从最新的年度登记报告中提取CRR和95%置信区间(CI)。对每个髋臼杯或股骨柄的CRR进行汇总,并研究髋臼杯与股骨柄组合之间以及登记处之间的差异。

结果

来自8个登记处的10个髋臼杯和8个股骨柄有CRR数据,共计552,148个髋臼杯和727,447个股骨柄。随访时间为1至20年。所有髋臼杯汇总的5年CRR为2.9%(95%CI:2.3 - 3.6),所有股骨柄汇总的5年CRR为3.0%(95%CI:2.4 - 3.8)。观察到两个髋臼杯和三个股骨柄在相关植入物和国家方面的CRR具有同质性(一致性)。仅在一个髋臼杯中发现相关植入物导致的CRR显著差异,仅在一个髋臼杯中发现登记处导致的CRR显著差异,在两个髋臼杯和四个股骨柄中发现两者均导致的CRR显著差异。数据稀少妨碍了对四个髋臼杯和一个股骨柄的评估。

结论

登记处的年度报告提供了大量关于特定植入物CRR的公开可用信息。这些CRR可以综合起来以改进对植入物长期性能的评估。我们的CRR分析是一种很有前景的方法,可用于检测各登记处中具有一致低风险或高风险模式的植入物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66d/12061013/8306f5f7022b/EOR-2024-0020fig1.jpg

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