Zarei-Ghanavati Siamak, Tabatabaei Seyed Mehdi, Gholamhoseinpour-Omran Samaneh, Hosseinikhah-Manshadi Hamed, Banan Saeed, Aminizade Mehdi, Esmaili Kosar, Azaripour Ebrahim
Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Korean J Ophthalmol. 2025 Jun;39(3):231-240. doi: 10.3341/kjo.2025.0016. Epub 2025 May 7.
To compare intraocular pressure (IOP) readings from corneas with intracorneal corneal ring segments (ICRS) using various methods, including Goldmann applanation tonometry (GAT), Tonopen, corneal-compensated IOP from the Ocular Response Analyzer (ORA), and biomechanically corrected IOP from the Corneal Visualization Scheimpflug Technology (Corvis ST).
This cross-sectional observational study included participants who had undergone ICRS implantation with KeraRing at least 3 months before the study. The mean IOP recorded by different instruments was compared using analysis of variance. Agreement among the methods was assessed with Bland-Altman plots.
A total of 54 eyes from 27 participants were enrolled. The mean IOP measured by Tonopen was significantly lower in the center compared to the peripheral quadrants (p < 0.001). IOP measured by GAT was significantly lower than that measured by Tonopen (13.02 ± 2.31 mmHg vs. 14.50 ± 2.91 mmHg, p = 0.021). There were no significant differences between the IOP measurements provided by Tonopen, ORA, and Corvis ST. The corneal-compensated IOP from ORA and biomechanically corrected IOP from Corvis ST had the highest correlation, with a weak intraclass correlation coefficient of 0.38.
IOP measurements using Tonopen were significantly lower in the central 5-mm zone compared to other quadrants. GAT measurements were significantly lower than those from Tonopen. Different measurement tools did not show a strong correlation. Corvis ST (biomechanically corrected IOP) tended to present lower readings at higher IOP levels in eyes with ICRS.
使用多种方法比较植入角膜内环片段（ICRS）的角膜的眼压（IOP）读数，这些方法包括Goldmann压平眼压计（GAT）、非接触眼压计（Tonopen）、眼反应分析仪（ORA）的角膜补偿眼压以及角膜可视化Scheimpflug技术（Corvis ST）的生物力学校正眼压。
这项横断面观察性研究纳入了在研究前至少3个月接受过KeraRing ICRS植入的参与者。使用方差分析比较不同仪器记录的平均眼压。通过Bland-Altman图评估这些方法之间的一致性。
共纳入了27名参与者的54只眼。与周边象限相比，Tonopen测量的中央平均眼压显著更低（p < 0.001）。GAT测量的眼压显著低于Tonopen测量的眼压（13.02±2.31 mmHg对14.50±2.91 mmHg，p = 0.021）。Tonopen、ORA和Corvis ST提供的眼压测量值之间无显著差异。ORA的角膜补偿眼压与Corvis ST的生物力学校正眼压具有最高的相关性，组内相关系数较弱，为0.38。
与其他象限相比，使用Tonopen测量的中央5毫米区域的眼压显著更低。GAT测量值显著低于Tonopen测量值。不同的测量工具未显示出强相关性。在植入ICRS的眼中，Corvis ST（生物力学校正眼压）在较高眼压水平下往往读数更低。
