Bamdad Shahram, Sedaghat Mohammad Reza, Yasemi Masoud, Maalhagh Mehrnoosh
Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Ophthalmology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
J Ophthalmol. 2020 Oct 7;2020:4274037. doi: 10.1155/2020/4274037. eCollection 2020.
The biomechanical properties of ecstatic cornea undergo changes. This study evaluates the biomechanical changes of ecstatic cornea after implantation of two types of intracorneal stromal ring (ICR).
For doing this prospective cross-sectional study, 32 patients with keratoconus (KCN) were randomly divided into two 16-member groups (group I: MyoRing, group II: KeraRing). The main inclusion criteria were transparent cornea with no scar in the central part, corneal thickness >450 in the incision region, keratometry within 48-52 diopters, and progressive course of corneal thinning. Biomechanics of the cornea was evaluated by "ORA" and "Corvis" devices. All of the data were recorded and analyzed before implantation of the rings and 6 months thereafter.
The mean ages of patients of groups I and II were 26 ± 6.55 and 33.86 ± 8.5, respectively. The postoperative change of sphere refraction was significant in both groups. However, reduction in the astigmatism was significant only in group I. In addition, the change of flat meridian keratometry (Kf) was significant before and after ring implantation in group I, unlike group II. The changes in CH and CRF parameters (ORA) were not significant in either group before and after the operation. Besides, only HRC parameter (Corvis) decreased significantly in both groups before and after the operation.
Both MyoRing and KeraRings have positive effects on the biomechanics of cornea at least during the first year after implantation. Comparison of these two types of ICR did not show significant differences in Corvis and ORA parameters.
圆锥角膜的生物力学特性会发生变化。本研究评估了两种类型的角膜基质内环(ICR)植入后圆锥角膜的生物力学变化。
为进行这项前瞻性横断面研究,32例圆锥角膜(KCN)患者被随机分为两个每组16人的组(I组:MyoRing,II组:KeraRing)。主要纳入标准为中央部分透明无瘢痕的角膜、切口区域角膜厚度>450μm、角膜曲率计测量值在48 - 52屈光度之间以及角膜变薄呈进行性发展。通过“ORA”和“Corvis”设备评估角膜生物力学。所有数据在环植入前及植入后6个月进行记录和分析。
I组和II组患者的平均年龄分别为26±6.55岁和33.86±8.5岁。两组术后球镜验光变化均显著。然而,仅I组散光降低显著。此外,与II组不同,I组环植入前后扁平子午线角膜曲率(Kf)变化显著。两组手术前后CH和CRF参数(ORA)变化均不显著。此外,两组手术前后仅HRC参数(Corvis)显著降低。
至少在植入后的第一年,MyoRing和KeraRing对角膜生物力学均有积极影响。这两种类型的ICR在Corvis和ORA参数方面比较未显示出显著差异。