Moomin Aliu, Gawusu Sidique, Sidik Abubakar Ibn, Tizumah Marizuk Waris, Adam Maridia Kunateh, Adu-Gyamfi Paa Kofi Tawiah, Mensah Kwesi Boadu
Rowett Institute, University of Aberdeen, Aberdeen, Scotland, UK.
Aberdeen Cancer Centre, University of Aberdeen, Aberdeen, Scotland, UK.
Biomed Res Int. 2025 Apr 29;2025:5086946. doi: 10.1155/bmri/5086946. eCollection 2025.
The global burden of cancer necessitates innovative approaches to its management and treatment. Traditional treatments like radiotherapy, immunotherapy, surgery, and chemotherapy, carry significant side effects that impact patient quality of life. Dietary fiber has attracted research interest as a potential mitigator of cancer progression and a supportive agent in cancer treatment. This bibliometric study analyzes trends in research connecting dietary fiber, cancer therapy, and gut health from April 1999 to May 2024. Web of Science, PubMed, and Scopus databases were used to retrieve peer-reviewed publications from April 1999 to May 2024 on dietary fiber and cancer management. The study identifies a rising scholarly interest in dietary fiber's role in cancer management, focusing significantly on the interactions between dietary fiber and gut microbiota. These interactions are particularly noted for their influence on inflammation and cancer metastasis. The study highlights evolving research themes, the importance of specific fiber types in cancer progression, and highlights persistent foundational themes like glycosylation. Emerging areas include personalized nutrition and innovative therapeutic approaches. The geographical and institutional contributions, mainly from the United States and China, underline the significance of collaborative and interdisciplinary efforts in advancing research. This analysis emphasizes integrating dietary strategies in comprehensive cancer care and aims to address research gaps to develop more effective and patient-centered cancer therapy and prevention strategies.
癌症的全球负担需要创新的管理和治疗方法。放疗、免疫疗法、手术和化疗等传统治疗方法会带来严重的副作用，影响患者的生活质量。膳食纤维作为癌症进展的潜在缓解因素和癌症治疗的辅助剂，已引起研究关注。这项文献计量研究分析了1999年4月至2024年5月期间将膳食纤维、癌症治疗和肠道健康联系起来的研究趋势。利用科学网、PubMed和Scopus数据库检索了1999年4月至2024年5月期间关于膳食纤维与癌症管理的同行评议出版物。该研究发现学术界对膳食纤维在癌症管理中的作用的兴趣日益浓厚，重点显著放在膳食纤维与肠道微生物群之间的相互作用上。这些相互作用因其对炎症和癌症转移的影响而尤为显著。该研究突出了不断演变的研究主题、特定纤维类型在癌症进展中的重要性，并强调了糖基化等持续的基础主题。新兴领域包括个性化营养和创新治疗方法。主要来自美国和中国的地理和机构贡献突显了合作和跨学科努力在推进研究方面的重要性。 这一分析强调在全面癌症护理中整合饮食策略，旨在填补研究空白，以制定更有效且以患者为中心的癌症治疗和预防策略。
