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老年人教育程度与血压之间的关联:对出生间隔20年的两代芬兰人群的研究

Association between educational attainment and blood pressure in older adults: a study of two Finnish generational cohorts born 20 years apart.

作者信息

Lääti Adriana, Somerpalo Oskari, Teppo Konsta, Vire Jenni, Viitanen Matti, Langén Ville

机构信息

Division of Medicine, Turku University Hospital and University of Turku, Turku, Finland, Kiinamyllynkatu 4-8, Turku, 20520, Finland.

Department of Geriatric Medicine, Turku University Hospital and University of Turku, Turku, Finland, Kunnallissairaalantie 20, Turku, 20700, Finland.

出版信息

Int J Cardiol Cardiovasc Risk Prev. 2025 Apr 22;25:200412. doi: 10.1016/j.ijcrp.2025.200412. eCollection 2025 Jun.

DOI:10.1016/j.ijcrp.2025.200412
PMID:40330155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12051710/
Abstract

BACKGROUND

This study compares the association between educational attainment and blood pressure (BP) in two Finnish cohorts of older adults, born 20 years apart.

METHODS

All 70-year-old residents of Turku, Finland, were surveyed in 1990 (1920-born TUVA cohort) and in 2010 (1940-born UTUVA cohort). Associations between education and BP were assessed using first ANOVA and post-hoc Tukey tests and then multiple linear regression, adjusted for age, gender, smoking, and body mass index. Analyses included 668 TUVA and 862 UTUVA participants.

RESULTS

In the TUVA cohort (67.7 % women, mean age 70.9), 77.7 % had primary education only, compared to 54.1 % in the UTUVA cohort (59.6 % women, mean age 71.4). ANOVA revealed a significant association between education level and diastolic BP in the UTUVA cohort (p = 0.04). All other ANOVA results were non-significant (p ≥ 0.14). Tertiary education did not have a significant association with BP (p ≥ 0.0544). In regression analyses, each additional year of education in UTUVA correlated with a 0.36 mmHg decrease in systolic BP (p = 0.01) and a 0.32 mmHg decrease in diastolic BP (p < 0.001).

CONCLUSIONS

The 1920-born cohort demonstrated no significant differences in BP across education levels, whereas in the cohort born in 1940, higher education was associated with significant but small reductions in BP. These findings suggest that education may be linked to BP, but the absolute differences across education levels are modest. The relationship between education and BP is complex, influenced by lifestyle choices and healthcare access, and requires further exploration.

摘要

背景

本研究比较了芬兰两个出生间隔20年的老年人群队列中受教育程度与血压(BP)之间的关联。

方法

1990年(出生于1920年的图瓦队列)和2010年(出生于1940年的乌图瓦队列)对芬兰图尔库所有70岁居民进行了调查。首先使用方差分析和事后 Tukey 检验评估教育与血压之间的关联,然后进行多元线性回归,并对年龄、性别、吸烟和体重指数进行调整。分析纳入了668名图瓦队列参与者和862名乌图瓦队列参与者。

结果

在图瓦队列(67.7%为女性,平均年龄70.9岁)中,77.7%的人仅接受过小学教育,而在乌图瓦队列(59.6%为女性,平均年龄71.4岁)中这一比例为54.1%。方差分析显示乌图瓦队列中教育水平与舒张压之间存在显著关联(p = 0.04)。所有其他方差分析结果均无统计学意义(p≥0.14)。高等教育与血压无显著关联(p≥0.0544)。在回归分析中,乌图瓦队列中每多接受一年教育,收缩压降低0.36 mmHg(p = 0.01),舒张压降低0.32 mmHg(p < 0.001)。

结论

出生于1920年的队列在不同教育水平的血压上无显著差异,而出生于1940年的队列中,高等教育与血压显著但小幅降低相关。这些发现表明教育可能与血压有关,但不同教育水平之间的绝对差异不大。教育与血压之间的关系复杂,受生活方式选择和医疗保健可及性影响,需要进一步探索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/3c4b1b2f152f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/d6b76c4d2c9b/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/8dc7a28ed213/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/c326f54e6c63/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/3c4b1b2f152f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/d6b76c4d2c9b/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/8dc7a28ed213/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/c326f54e6c63/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f49/12051710/3c4b1b2f152f/gr3.jpg

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本文引用的文献

1
The natural history of hypertension in older adults: a study of two Finnish generational cohorts born 20 years apart.老年人高血压的自然史:一项芬兰隔代出生的两代人研究。
Blood Press. 2024 Dec;33(1):2368798. doi: 10.1080/08037051.2024.2368798. Epub 2024 Jun 24.
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Independent Associations of Education, Intelligence, and Cognition With Hypertension and the Mediating Effects of Cardiometabolic Risk Factors: A Mendelian Randomization Study.教育、智力和认知与高血压的独立关联及其与心血管代谢风险因素的中介作用:一项孟德尔随机化研究。
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The Association of Socioeconomic Status With Hypertension in 76 Low- and Middle-Income Countries.
76 个中低收入国家的社会经济地位与高血压的关系。
J Am Coll Cardiol. 2022 Aug 23;80(8):804-817. doi: 10.1016/j.jacc.2022.05.044.
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