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视频观察疗法用于结核病治疗监测的有效性和可接受性:一项范围综述

Effectiveness and Acceptability of Video-Observed Therapy for Tuberculosis Treatment Monitoring: A Scoping Review.

作者信息

Othman Rahayu, Safian Nazarudin, Hassan Mohd Rohaizat

机构信息

Department of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Kuala Lumpur, Malaysia.

出版信息

Iran J Public Health. 2025 Mar;54(3):499-508. doi: 10.18502/ijph.v54i3.18243.

Abstract

BACKGROUND

Tuberculosis (TB) control programs confront a significant challenge in ensuring patients fully adhere to their treatment regimens. Video-observed therapy (VOT) is an alternative digital technology for monitoring tuberculosis treatment that may potentially improve adherence and clinical outcomes. However, there is limited evidence supporting the effectiveness and acceptability of VOT. This scoping review aimed to summarize the characteristics of existing evidence-based VOT for tuberculosis treatment monitoring and to describe the evidence for their effectiveness and acceptability.

METHODS

This review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for scoping review protocol in Jan 2023. Three databases, namely PubMed, Web of Science, and SCOPUS, were used in this review.

RESULTS

The search identified 170 articles, and after the identification and screening process, 22 articles were included in this review. The findings were categorized into effectiveness and acceptability.

CONCLUSION

There is a progressively growing body of evidence, particularly in treating and monitoring TB using VOT, which has a positive impact on improving effectiveness regarding health outcomes and is widely accepted to implement. Future studies, such as non-inferiority trials and cost-effectiveness evaluations, will help improve tuberculosis strategies and management.

摘要

背景

结核病控制项目在确保患者完全遵守治疗方案方面面临重大挑战。视频观察治疗(VOT)是一种用于监测结核病治疗的替代性数字技术,可能会提高依从性和临床结局。然而,支持VOT有效性和可接受性的证据有限。本综述旨在总结现有基于证据的VOT用于结核病治疗监测的特征,并描述其有效性和可接受性的证据。

方法

本综述于2023年1月使用系统评价和Meta分析的首选报告项目(PRISMA)扩展版进行范围综述。本综述使用了三个数据库,即PubMed、科学网和Scopus。

结果

检索到170篇文章,经过识别和筛选过程,本综述纳入了22篇文章。研究结果分为有效性和可接受性两类。

结论

证据越来越多,特别是在使用VOT治疗和监测结核病方面,这对改善健康结局的有效性有积极影响,并且被广泛接受实施。未来的研究,如非劣效性试验和成本效益评估,将有助于改进结核病策略和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb7/12051805/74f2dc09d791/IJPH-54-499-g001.jpg

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