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创伤诱发头皮隆突性皮肤纤维肉瘤复发:1例6年随访病例报告及文献复习

Trauma-induced recurrent of scalp dermatofibrosarcoma protuberans: a case report with a 6-year follow-up and literature review.

作者信息

Ouyang Qian, Zhou Yuxiang, Huang Yongkai

机构信息

Department of Neurosurgery, Zhuzhou Hospital, Central South University Xiangya School of Medicine, Zhuzhou, China.

出版信息

AME Case Rep. 2025 Mar 4;9:48. doi: 10.21037/acr-24-187. eCollection 2025.

Abstract

BACKGROUND

Dermatofibrosarcoma protuberans (DFSP) is a rare mesenchymal cell-derived soft tissue tumor, especially on the scalp. As a result, there is a lack of insight into the etiology of its occurrence and the triggers of its recurrence, which makes diagnosis difficult. This paper reports a case with a long follow-up period in an attempt to provide some valuable evidence-based medicine to assist in the clinical work-up of diagnostic.

CASE DESCRIPTION

We selected a young male who underwent surgical treatment in our hospital in 2013, and his pathological result at that time was "suspected dermatofibrosarcoma protuberans". At the same time, we followed the patient for 6 years and performed a literature review on the current management of DFSP. Six years later, the patient's scalp mass recurred after a head trauma. Based on the patient's medical history and pathogenesis of the disease, we believe that the patient's disease may be related to trauma.

CONCLUSIONS

DFSP is rare in clinic, and it is easy to be misdiagnosed because of its atypical clinical symptoms and long diagnosis time. This article analyzed the case which has a long-time follow-up and reviewed the literature on DFSP. Therefore, this paper finds that trauma may be a causative factor in the development and recurrence, and provides a basis for evidence-based medicine for the diagnosis and treatment of this disease.

摘要

背景

隆突性皮肤纤维肉瘤(DFSP)是一种罕见的间充质细胞来源的软组织肿瘤,尤其好发于头皮。因此,对其发病原因及复发诱因缺乏深入了解,导致诊断困难。本文报告一例随访时间较长的病例,旨在提供一些有价值的循证医学依据,以协助DFSP的临床诊断工作。

病例描述

我们选取了一名于2013年在我院接受手术治疗的青年男性,其当时的病理结果为“疑似隆突性皮肤纤维肉瘤”。同时,我们对该患者进行了6年的随访,并对DFSP的当前治疗方法进行了文献综述。6年后,该患者头部外伤后头皮肿物复发。基于患者的病史及疾病发病机制,我们认为该患者的病情可能与外伤有关。

结论

DFSP在临床上较为罕见,因其临床症状不典型且诊断时间长,容易被误诊。本文对该例进行了长时间随访并对DFSP相关文献进行了综述。因此,本文发现外伤可能是其发生及复发的一个致病因素,为该病的诊断和治疗提供了循证医学依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/12053716/e970f47d3249/acr-09-24-187-f1.jpg

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