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Home oxygen therapy for Thai preterm infants with bronchopulmonary dysplasia. What are the predictive factors for successful weaning: a 20-year review.泰国支气管肺发育不良早产儿的家庭氧疗。成功撤机的预测因素有哪些:一项20年的回顾。
BMC Pediatr. 2025 Jan 11;25(1):25. doi: 10.1186/s12887-024-05354-1.
2
Strategies for the prevention of bronchopulmonary dysplasia.预防支气管肺发育不良的策略。
Front Pediatr. 2024 Jul 24;12:1439265. doi: 10.3389/fped.2024.1439265. eCollection 2024.
3
Characteristics of home oxygen therapy for preterm infants with bronchopulmonary dysplasia in China: results of a multicenter cohort study.中国支气管肺发育不良早产儿家庭氧疗的特点:多中心队列研究的结果。
World J Pediatr. 2023 Jun;19(6):557-567. doi: 10.1007/s12519-022-00591-9. Epub 2022 Aug 11.
4
Duration of mechanical ventilation and prediction of bronchopulmonary dysplasia and home oxygen in extremely preterm infants.机械通气时间与极早产儿支气管肺发育不良和家庭吸氧预测的关系。
Acta Paediatr. 2021 Jul;110(7):2052-2058. doi: 10.1111/apa.15801. Epub 2021 Feb 15.
5
Neurodevelopmental outcomes of very low birth weight infants in the Neonatal Research Network of Japan: importance of neonatal intensive care unit graduate follow-up.日本新生儿研究网络中极低出生体重儿的神经发育结局:新生儿重症监护病房出院后随访的重要性
Clin Exp Pediatr. 2021 Jul;64(7):313-321. doi: 10.3345/cep.2020.01312. Epub 2020 Nov 9.
6
Neurodevelopmental outcomes of preterm infants: a recent literature review.早产儿的神经发育结局:近期文献综述
Transl Pediatr. 2020 Feb;9(Suppl 1):S3-S8. doi: 10.21037/tp.2019.09.10.
7
Home Oxygen Use and 1-Year Readmission among Infants Born Preterm with Bronchopulmonary Dysplasia Discharged from Children's Hospital Neonatal Intensive Care Units.早产儿支气管肺发育不良患儿出院后家庭氧疗使用与 1 年再入院的关系
J Pediatr. 2020 May;220:40-48.e5. doi: 10.1016/j.jpeds.2020.01.018. Epub 2020 Feb 21.
8
Trends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries.11 个高收入国家中极早产和极低出生体重儿结局的变化趋势。
J Pediatr. 2019 Dec;215:32-40.e14. doi: 10.1016/j.jpeds.2019.08.020. Epub 2019 Oct 3.
9
Morbidity and mortality of very low birth weight infants in Taiwan-Changes in 15 years: A population based study.台湾极低出生体重婴儿的发病率和死亡率:15年的变化——一项基于人群的研究
J Formos Med Assoc. 2016 Dec;115(12):1039-1045. doi: 10.1016/j.jfma.2016.10.011. Epub 2016 Dec 9.
10
Early neurodevelopmental outcomes of extremely preterm infants.极早早产儿的早期神经发育结局
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极低出生体重早产儿出院后的医疗需求:一项基于台湾地区人群的研究。

Medical Needs of Very-Low-Birth-Weight Preterm Infants Post-Discharge: A Population-Based Study in Taiwan.

作者信息

Chang Jui-Hsing, Chen Chia-Huei, Peng Chun-Chih, Lin Chia-Ying, Chang Hung-Yang, Hsu Chyong-Hsin, Jim Wai-Tim

机构信息

Division of Neonatology, Department of Pediatrics, MacKay Children's Hospital, Taipei City, Taiwan.

Department of Medicine, MacKay Medical College, New Taipei City, Taiwan.

出版信息

Neonatology. 2025 May 7:1-9. doi: 10.1159/000546115.

DOI:10.1159/000546115
PMID:40334647
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12187098/
Abstract

INTRODUCTION

The aim of this study was to explore the outcomes, home use of medical assistive devices, and interdisciplinary medical needs of very-low-birth-weight (VLBW) infants at a corrected age of 2 years.

METHODS

Analyses were performed using perinatal, neonatal, and 2-year follow-up data from VLBW infants registered in the Taiwan Premature Infant Follow-up Network (TPFN) between 2011 and 2017. Basic information, survival, and disease conditions during hospitalization were recorded. Medical needs at discharge, outcomes at a corrected age of 2 years, active involvement in outpatient healthcare services, and referrals were investigated.

RESULTS

From 2011 to 2017, a total of 9,243 VLBW preterm neonates were enrolled in the TPFN. Of these neonates, 140 had severe congenital anomalies, 8,044 survived to discharge, and 6,150 returned for follow-up evaluation. At discharge, 10.2% of infants received home oxygen therapy (HOT), and 6.5% used home monitoring devices. Among the infants diagnosed with chronic lung disease, 26.6% received HOT. At a corrected age of 2 years, the most common interventions and recommended referrals were rehabilitative treatments (34.5%), followed by early intervention system services (16.5%), ophthalmology/otolaryngology management (4.4%), neurological follow-up (4.1%), and mental health assessment and treatment (2.5%).

CONCLUSION

After hospital discharge, VLBW preterm infants exhibit substantial healthcare needs, with significant demands of HOT, rehabilitation, and early intervention services by a corrected age of 2 years. These findings highlight the importance of coordinated outpatient care and long-term follow-up to address the developmental and medical challenges faced by this vulnerable population.

摘要

引言

本研究旨在探讨极低出生体重(VLBW)婴儿在2岁矫正年龄时的预后、医疗辅助设备的家庭使用情况以及跨学科医疗需求。

方法

利用2011年至2017年在台湾早产儿随访网络(TPFN)登记的VLBW婴儿的围产期、新生儿期和2年随访数据进行分析。记录基本信息、住院期间的生存情况和疾病状况。调查出院时的医疗需求、2岁矫正年龄时的预后、积极参与门诊医疗服务的情况以及转诊情况。

结果

2011年至2017年,共有9243例VLBW早产儿纳入TPFN。其中,140例有严重先天性异常,8044例存活至出院,6150例返回进行随访评估。出院时,10.2%的婴儿接受家庭氧疗(HOT),6.5%使用家庭监测设备。在被诊断为慢性肺病的婴儿中,26.6%接受HOT。在2岁矫正年龄时,最常见的干预措施和推荐转诊是康复治疗(34.5%),其次是早期干预系统服务(16.5%)、眼科/耳鼻喉科管理(4.4%)、神经学随访(4.1%)以及心理健康评估和治疗(2.5%)。

结论

出院后,VLBW早产儿表现出大量的医疗需求,在2岁矫正年龄时对HOT、康复和早期干预服务有显著需求。这些发现凸显了协调门诊护理和长期随访以应对这一脆弱人群所面临的发育和医疗挑战的重要性。