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本文引用的文献

1
The Most Current Algorithms for the Treatment and Prevention of Hypertrophic Scars and Keloids: A 2020 Update of the Algorithms Published 10 Years Ago.治疗和预防增生性瘢痕和瘢痕疙瘩的最新算法:10 年前发布的算法的 2020 年更新。
Plast Reconstr Surg. 2022 Jan 1;149(1):79e-94e. doi: 10.1097/PRS.0000000000008667.
2
Timing of Adjuvant Radiotherapy After Keloid Excision: A Systematic Review and Meta-Analysis.瘢痕疙瘩切除术后辅助放疗时机:系统评价和荟萃分析。
Dermatol Surg. 2021 Nov 1;47(11):1438-1443. doi: 10.1097/DSS.0000000000003165.
3
A Retrospective Registry Study Evaluating the Long-Term Efficacy and Safety of Superficial Radiation Therapy Following Excision of Keloid Scars.一项评估瘢痕疙瘩切除术后浅表放射治疗长期疗效和安全性的回顾性登记研究。
J Clin Aesthet Dermatol. 2020 Oct;13(10):12-16. Epub 2020 Oct 1.
4
Risk factors of recurrence after postoperative electron beam radiation therapy for keloid: Comparison of long-term local control rate.瘢痕疙瘩术后电子束放射治疗后复发的危险因素:长期局部控制率的比较。
Rep Pract Oncol Radiother. 2020 Jul-Aug;25(4):606-611. doi: 10.1016/j.rpor.2020.05.001. Epub 2020 May 19.
5
Location Propensity for Keloids in the Head and Neck.头部和颈部瘢痕疙瘩的位置倾向。
Facial Plast Surg Aesthet Med. 2021 Jan-Feb;23(1):59-64. doi: 10.1089/fpsam.2020.0106. Epub 2020 Jun 8.
6
Sex Differences in Keloidogenesis: An Analysis of 1659 Keloid Patients in Japan.瘢痕疙瘩形成中的性别差异:对日本1659例瘢痕疙瘩患者的分析。
Dermatol Ther (Heidelb). 2019 Dec;9(4):747-754. doi: 10.1007/s13555-019-00327-0. Epub 2019 Oct 4.
7
Analyses of size and computed tomography densitometry parameters for prediction of keloid recurrence after postoperative electron beam radiation therapy.分析尺寸及计算机断层扫描密度测定参数以预测术后电子束放射治疗后瘢痕疙瘩复发情况。
Skin Res Technol. 2020 Jan;26(1):125-131. doi: 10.1111/srt.12775. Epub 2019 Sep 23.
8
Dose Effect in Adjuvant Radiation Therapy for the Treatment of Resected Keloids.辅助放疗治疗切除后瘢痕疙瘩的剂量效应。
Int J Radiat Oncol Biol Phys. 2018 Sep 1;102(1):149-154. doi: 10.1016/j.ijrobp.2018.05.027. Epub 2018 May 17.
9
Optimal High-Dose-Rate Brachytherapy Fractionation Scheme After Keloid Excision: A Retrospective Multicenter Comparison of Recurrence Rates and Complications.优化的高剂量率近距离放疗分割方案在瘢痕疙瘩切除术后的应用:复发率和并发症的回顾性多中心比较。
Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):679-686. doi: 10.1016/j.ijrobp.2017.10.044. Epub 2017 Nov 4.
10
Current Understanding of the Genetic Causes of Keloid Formation.瘢痕疙瘩形成遗传原因的当前认识。
J Investig Dermatol Symp Proc. 2017 Oct;18(2):S50-S53. doi: 10.1016/j.jisp.2016.10.024.

手术切除联合电子束治疗瘢痕疙瘩的疗效分析

Analysis of the Efficacy of Surgical Excision Combined with Electron Beam Therapy for Keloids.

作者信息

Zhang Jiaqi, Jeon Dongjun, Su Zheng, Xiao Xiaolian, Zhang Jinming, Liang Weiqiang

机构信息

Department of Plastic Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 Yanjiang West Road, Guangzhou, China.

出版信息

Indian J Surg Oncol. 2025 Apr;16(2):550-557. doi: 10.1007/s13193-024-02048-z. Epub 2024 Oct 2.

DOI:10.1007/s13193-024-02048-z
PMID:40337020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12052671/
Abstract

This study aimed to investigate the incidence and impact of patient characteristics and timing of postoperative electron beam therapy on the treatment efficacy of keloids. A total of 66 patients with keloids underwent surgical treatment and postoperative electron beam therapy. Follow-up was conducted for 43 patients, and treatment efficacy was analyzed for 39 patients. Statistical analysis was used to analyze incidence characteristics and effects of patient characteristics and timing of electron beam therapy on treatment efficacy. The study included 66 patients with 133 keloids. The timing of electron beam therapy significantly impacted treatment efficacy, with higher efficacy observed when performed 0-2 days after surgery compared to 3-5 days after surgery. Keloids are more common in women aged 20-40 years. The timing of electron beam therapy significantly impacted treatment efficacy, with higher efficacy observed when performed 0-2 days after surgery compared to 3-5 days after surgery.

摘要

本研究旨在调查患者特征及术后电子束治疗时机对瘢痕疙瘩治疗效果的发生率及影响。共有66例瘢痕疙瘩患者接受了手术治疗及术后电子束治疗。对43例患者进行了随访,对39例患者的治疗效果进行了分析。采用统计学分析来分析患者特征及电子束治疗时机对治疗效果的发生率特征及影响。该研究纳入了66例患者的133个瘢痕疙瘩。电子束治疗时机对治疗效果有显著影响,与术后3 - 5天进行治疗相比,术后0 - 2天进行治疗时观察到更高的疗效。瘢痕疙瘩在20 - 40岁女性中更为常见。电子束治疗时机对治疗效果有显著影响,与术后3 - 5天进行治疗相比,术后0 - 2天进行治疗时观察到更高的疗效。