Negi Sakshi, Panda Naresh Kumar, Patro Sourabha Kumar, Gupta Rijuneeta, Parsana Monil, Saxena Shivam, Chatterjee Debajyoti, Iangngap Elgiva Khristie
Department of Otolaryngology and Head & Neck Surgery, PGIMER Chandigarh, Chandigarh, India.
Department of Histopathology, PGIMER Chandigarh, Chandigarh, India.
Indian J Surg Oncol. 2025 Apr;16(2):633-638. doi: 10.1007/s13193-024-02111-9. Epub 2024 Oct 25.
Carcinoma arising from the thyroglossal duct cysts is a rare entity which results from metaplastic changes in the persistent thyroglossal duct. This study highlights five cases of thyroglossal duct carcinoma accompanied by thyroid malignancy in three cases. Papillary carcinoma is the predominant subtype, observed in all five cases. Sistrunk surgery, combined with total thyroidectomy, was performed on all patients, with one patient undergoing additional neck dissection. Thyroglossal duct papillary carcinoma is relatively uncommon condition and its co-occurrence with thyroid gland carcinoma further adds to its rarity which required surgical management followed by radioactive iodine ablation therapy with thyroid hormone suppression. Timely identification, coupled with appropriate surgical intervention, is necessary for favourable patient's outcomes. Additional procedures, such as total thyroidectomy when necessary and neck dissection, should be considered.
起源于甲状舌管囊肿的癌是一种罕见的疾病，它由残留甲状舌管的化生改变引起。本研究重点介绍了5例甲状舌管癌，其中3例伴有甲状腺恶性肿瘤。乳头状癌是主要的亚型，5例均有此表现。所有患者均接受了Sistrunk手术联合甲状腺全切除术，1例患者还接受了颈部淋巴结清扫术。甲状舌管乳头状癌相对少见，其与甲状腺癌同时出现更是罕见，需要手术治疗，随后进行放射性碘消融治疗及甲状腺激素抑制治疗。及时识别并进行适当的手术干预，对于患者获得良好预后是必要的。应考虑采取其他手术，如必要时进行甲状腺全切除术及颈部淋巴结清扫术。
