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单侧右甲状腺肿大伴对侧左纵隔良性异位甲状腺组织肿块:一例罕见病例报告

Unilateral right thyroid swelling with contralateral left mediastinal mass of benign ectopic thyroid tissue: a rare case report.

作者信息

Sajjad Waseem, Bin Aziz Hassan, Tabasum Pakeezah, Maryam Alam Syeda, Mufti Muttayab Serwan, Iqbal Javed

机构信息

King Edward Medical University, Mayo Hospital, Lahore, Pakistan.

Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan.

出版信息

Ann Med Surg (Lond). 2025 Apr 4;87(5):2982-2986. doi: 10.1097/MS9.0000000000002993. eCollection 2025 May.

DOI:10.1097/MS9.0000000000002993
PMID:40337387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12055109/
Abstract

INTRODUCTION AND IMPORTANCE

Ectopic thyroid is a very rare developmental anomaly with difficult diagnostic challenges, especially when located away from its normal anatomical pathway of development and descent. The coexistence of a unilateral thyroid enlargement with a mass in the thoracic region is very rare and can resemble malignancies and tumors complicating the process of diagnosis and management.

CASE PRESENTATION

A 44-year-old female presented with a unilateral right thyroid swelling, with further investigation revealing a left mediastinal mass. Initial imaging and biopsy raised concerns about possible malignancy. However, a surgical biopsy confirmed benign ectopic thyroid tissue. The patient underwent total thyroidectomy and excision of the mediastinal mass, recovering without complications.

CLINICAL DISCUSSION

This case reports a rare coexistence of thyroid swelling and ectopic thyroid in the mediastinum. An extensive diagnostic protocol is mandatory to exclude any potential malignancies. Careful surgical management is required for optimal outcomes and the long-term well-being of the patient.

CONCLUSION

This case report emphasizes the significance of considering ectopic thyroid as a differential diagnosis of mediastinal masses. This case report presents information that not only helps to prevent misdiagnosis but also guide on the suitable treatment and management.

摘要

引言与重要性

异位甲状腺是一种非常罕见的发育异常,诊断具有挑战性,尤其是当它位于正常发育和下降的解剖路径之外时。单侧甲状腺肿大并伴有胸部肿块的情况非常罕见,可能类似于恶性肿瘤,从而使诊断和治疗过程复杂化。

病例介绍

一名44岁女性出现右侧甲状腺单侧肿大,进一步检查发现左纵隔有肿块。最初的影像学检查和活检引发了对可能恶性肿瘤的担忧。然而,手术活检证实为良性异位甲状腺组织。患者接受了全甲状腺切除术和纵隔肿块切除术,术后恢复良好,无并发症。

临床讨论

本病例报告了甲状腺肿大与纵隔异位甲状腺罕见的并存情况。必须采用广泛的诊断方案以排除任何潜在的恶性肿瘤。为了获得最佳结果和患者的长期健康,需要进行仔细的手术管理。

结论

本病例报告强调了将异位甲状腺作为纵隔肿块鉴别诊断的重要性。本病例报告提供的信息不仅有助于防止误诊,还能指导合适的治疗和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/9deb9c4c9bcf/ms9-87-2982-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/88ed4590bb66/ms9-87-2982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/7b27fc635ac6/ms9-87-2982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/ceff293818bd/ms9-87-2982-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/55548aba3042/ms9-87-2982-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/d6739cca3dbb/ms9-87-2982-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/9deb9c4c9bcf/ms9-87-2982-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/88ed4590bb66/ms9-87-2982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/7b27fc635ac6/ms9-87-2982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/ceff293818bd/ms9-87-2982-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/55548aba3042/ms9-87-2982-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/d6739cca3dbb/ms9-87-2982-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd8/12055109/9deb9c4c9bcf/ms9-87-2982-g006.jpg

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本文引用的文献

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The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
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Ectopic thyroid tissue in the anterior mediastinum along with a normally located gland.前纵隔内的异位甲状腺组织以及位置正常的甲状腺。
Radiol Case Rep. 2021 Aug 26;16(11):3191-3195. doi: 10.1016/j.radcr.2021.07.064. eCollection 2021 Nov.
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Levothyroxine Therapy in Thyrodectomized Patients.甲状腺切除术患者的左甲状腺素治疗。
Front Endocrinol (Lausanne). 2021 Jan 29;11:626268. doi: 10.3389/fendo.2020.626268. eCollection 2020.
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Submental Ectopic Thyroid Cyst: An Atypical Presentation.颏下异位甲状腺囊肿:一种非典型表现。
Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):712-715. doi: 10.1007/s12070-018-1515-0. Epub 2018 Oct 30.
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Ectopic thyroid: The great mimicker.异位甲状腺:极具迷惑性的病症。
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