Yang Tong-Jie, Wen Peng-Peng, Chen Tian-Xin, Zhang Guang-Yi, Dong Ya-Wei, Sun Yi-Fei, Huang Zhi-Jian, Gao Rui, Du Peng-Cheng, He Hai-Jun
Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, Zhejiang Province, China.
Ann Med Surg (Lond). 2025 Apr 4;87(5):2718-2735. doi: 10.1097/MS9.0000000000003110. eCollection 2025 May.
Osteonecrosis of the femoral head (ONFH), caused by disrupted blood supply leading to bone cell death and joint collapse, remains a critical orthopedic challenge. While core decompression has advanced significantly in ONFH treatment, no bibliometric analysis has mapped its research landscape.
We analyzed 854 articles from the Web of Science Core Collection (1986-2023) using VOSviewer, CiteSpace, and bibliometrix.
Publications surged from 5.4/year (1986-2001) to 52.3/year (2015-2023), reflecting intensified interest. China (253 articles, 29.6%) and the United States (232, 27.2%) dominated contributions, with Stanford University and Johns Hopkins University as top institutions. International collaborations linked China to the United States, Germany, and England. was the most cited journal (4708 citations). Keyword analysis revealed emerging hotspots: mesenchymal stem cells (19 occurrences), cell therapy, and angiogenesis. Citation bursts highlighted Mont MA's seminal work (burst strength: 19.67) on joint-preserving strategies and stem cell-enhanced core decompression.
This first bibliometric study delineates trends, collaborations, and frontiers in core decompression for ONFH, emphasizing the translational potential of stem cell therapies.
股骨头坏死(ONFH)是由于血液供应中断导致骨细胞死亡和关节塌陷引起的,仍然是骨科领域的一项严峻挑战。虽然核心减压术在ONFH治疗方面已经取得了显著进展,但尚未有文献计量分析描绘其研究格局。
我们使用VOSviewer、CiteSpace和bibliometrix分析了来自科学网核心合集(1986 - 2023年)的854篇文章。
出版物数量从每年5.4篇(1986 - 2001年)激增至每年52.3篇(2015 - 2023年),反映出人们对此兴趣增强。中国(253篇文章,占29.6%)和美国(232篇,占27.2%)贡献最大,斯坦福大学和约翰霍普金斯大学是顶尖机构。国际合作将中国与美国、德国和英国联系起来。《 》是被引用次数最多的期刊(4708次引用)。关键词分析揭示了新出现的热点:间充质干细胞(出现19次)、细胞治疗和血管生成。引用爆发突出了Mont MA关于保关节策略和干细胞增强核心减压的开创性工作(爆发强度:19.67)。
这项首次进行的文献计量研究描绘了ONFH核心减压术的趋势、合作和前沿,强调了干细胞疗法的转化潜力。