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足部软骨母细胞瘤:来自单一机构的40例病例

Chondroblastoma of the Foot: 40 Cases From a Single Institution.

作者信息

Angelini Andrea, Arguedas Fabricio, Varela Andrès, Ruggieri Pietro

机构信息

Associate Professor, Department of Orthopedic and Orthopedic Oncology, University of Padova, Italy.

Medical Doctor, Fellow at II Department of Orthopedics, University of Bologna, Rizzoli Orthopaedic Institute, Bologna, Italy.

出版信息

J Foot Ankle Surg. 2018 Nov-Dec;57(6):1105-1109. doi: 10.1053/j.jfas.2018.05.005.

DOI:10.1053/j.jfas.2018.05.005
PMID:30368424
Abstract

Chondroblastoma (CB) of the foot is a rare lesion. The purpose of this report was to report a large series from a single institution to analyze clinical, radiographic, and histologic characteristics; treatment; and local recurrence. We present 40 patients (30 males, 10 females; mean age 25 years) diagnosed and treated for CB of the foot from 1975 to 2012. The mean follow-up visit was 55 months (range 7 months to 11 years). Clinical presentation, histology, imaging, surgical treatment, and local recurrence were evaluated. Males were more affected than females. The main symptom was pain (100%) accompanied by swelling (35%), with median duration of 12 months. The talus (50%) and calcaneus (37.5%) were the most affected bones. All patients underwent surgery: curettage (10 cases), curettage and bone graft (15 cases), curettage and cement (13 cases), wide resection (1 case), and Chopart amputation (1 case). Ten patients (25%) had secondary aneurysmal bone cyst. One patient had local recurrence after surgery. In conclusion, patients with CB of the foot are usually older than 20 years, and males are most affected. The hindfoot is the most affected area. Surgical treatment is required, and intralesional curettage and packing with cement or graft is curative in most cases. Local recurrence in foot is lower than in other locations.

摘要

足部软骨母细胞瘤(CB)是一种罕见的病变。本报告的目的是报告来自单一机构的一大系列病例,以分析其临床、影像学和组织学特征、治疗方法以及局部复发情况。我们呈现了1975年至2012年期间诊断并接受治疗的40例足部CB患者(男性30例,女性10例;平均年龄25岁)。平均随访时间为55个月(范围7个月至11年)。对临床表现、组织学、影像学、手术治疗和局部复发情况进行了评估。男性比女性更易受累。主要症状为疼痛(100%),伴有肿胀(35%),中位病程为12个月。距骨(50%)和跟骨(37.5%)是最常受累的骨骼。所有患者均接受了手术:刮除术(10例)、刮除术加植骨(15例)、刮除术加骨水泥填充(13例)、广泛切除术(1例)和Chopart截肢术(1例)。10例患者(25%)继发动脉瘤样骨囊肿。1例患者术后出现局部复发。总之,足部CB患者通常年龄大于20岁,男性受累最多。后足是最常受累的部位。需要进行手术治疗,大多数情况下病灶内刮除并填充骨水泥或植骨可治愈。足部的局部复发率低于其他部位。

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