Negri M, Riva M, Broccolino M, Volpi M, Galbiati N
Minerva Med. 1985 Sep 15;76(34-35):1521-7.
Ten risk factors (RF) were sought and compared in 100 patients with acute myocardial infarct (MI) and 50 with cerebrovascular disease (CVD) on their first admission. No other diseases were present. Only 3 subjects were free of the RF. At least three RF were noted in 71 MI (71%) and 32 CVD (64%), and four or more in 51 (51%) and 22 (44%) respectively. The most commonly observed in both groups were: high total: HDL cholesterol ratio, cigarette smoking, hypertriglyceridaemia, arterial hypertension, hyperuricaemia Total blood cholesterol was more frequently above normal in MI (52%) than CVD (28%). The difference between the means was significant (p less than 0.01). No significant differences, on the other hand, were noted for the other RF. These findings suggest that the definition of RF for MI and CVD patients is both practicable and important in the secondary prevention of these two diseases. They also show that their atherosclerotic risk profile is substantially the same.
在100例首次入院的急性心肌梗死（MI）患者和50例脑血管疾病（CVD）患者中，寻找并比较了10种风险因素（RF）。这些患者无其他疾病。只有3名受试者无风险因素。71例（71%）MI患者和32例（64%）CVD患者至少有三种风险因素，51例（51%）MI患者和22例（44%）CVD患者有四种或更多风险因素。两组中最常见的风险因素是：总胆固醇与高密度脂蛋白胆固醇比值高、吸烟、高甘油三酯血症、动脉高血压、高尿酸血症。MI患者（52%）总血胆固醇高于正常的情况比CVD患者（28%）更常见。均值差异具有显著性（p<0.01）。另一方面，其他风险因素未发现显著差异。这些发现表明，MI和CVD患者风险因素的定义在这两种疾病的二级预防中既可行又重要。它们还表明，这两类患者的动脉粥样硬化风险状况基本相同。
