Augsburger J J, Shields J A
Ophthalmology. 1985 Jun;92(6):815-22. doi: 10.1016/s0161-6420(85)33955-6.
We reviewed the records of thirteen patients with posterior uveal malignant melanoma who had developed a mature radiation cataract following cobalt-60 plaque radiotherapy. Cataract extraction had been performed in seven of these patients as of the survey date of this investigation. We attempted to determine if cataract extraction increased the risk of metastatic melanoma, improved or worsened visual function, or resulted in any consistent intraoperative or postoperative complications that did not occur if the cataract was retained. Our analysis showed that removing the cataract did not appear to increase the risk of death from metastatic melanoma, but it also indicated that cataract extraction did not seem to improve the visual function of the irradiated eye. On the basis of our experience to date, we offer suggested guidelines for the management of patients who develop a mature cataract following cobalt-60 plaque radiotherapy of a posterior uveal malignant melanoma.
我们回顾了13例后葡萄膜恶性黑色素瘤患者的病历，这些患者在接受钴-60敷贴放射治疗后出现了成熟的放射性白内障。截至本次调查的统计日期，其中7例患者已接受了白内障摘除术。我们试图确定白内障摘除是否会增加转移性黑色素瘤的风险，改善或恶化视觉功能，或者是否会导致任何在保留白内障时不会出现的一致的术中或术后并发症。我们的分析表明，摘除白内障似乎不会增加转移性黑色素瘤导致死亡的风险，但也表明白内障摘除似乎并未改善受照射眼的视觉功能。根据我们目前的经验，我们为后葡萄膜恶性黑色素瘤接受钴-60敷贴放射治疗后出现成熟白内障的患者提供了管理建议指南。
