Aghabeygiha Mehrnoosh, Fahimzad Seyed Alireza, Behzad Shima, Zadeh Rasoul Hossein, Sheikhzadeh Farzad, Tamaddon Yasaman, Hajipour Mahmoud, Zadeh Reza Hossein, Neyriz Ali, Pak Neda, Shirvani Armin, Hosseini Amirhossein, Khalili Mitra
School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
School of Medicine, Islamic Azad University of Medical Sciences, Tehran, Iran.
Front Radiol. 2025 Apr 24;5:1571672. doi: 10.3389/fradi.2025.1571672. eCollection 2025.
COVID-19 has emerged as a global pandemic affecting individuals of all ages. The disease can lead to severe complications and even death, particularly due to pulmonary involvement. Contrary to popular belief, children can also experience significant complications from COVID-19. To date, there have been limited studies focusing on pulmonary manifestations in pediatric patients with COVID-19. This study aims to investigate the imaging patterns (CT scans) in children diagnosed with COVID-19 in Iran.
This retrospective study analyzed data from hospitalized children with COVID-19 in Tehran from March 2020 to September 2020. Information collected included demographic details (sex and age), previous medical history, clinical manifestations, vital signs at admission, laboratory findings, and imaging results, including CT scan and chest x-ray.
252 patients were included, with a mean age of 71.2 ± 59.42 months; 58.3% were male. Fever was the most prevalent symptom, occurring in 67.4% of cases. The most common underlying condition was oncological disorders, present in 85% of patients. Notably, 52% required admission to the ICU, and 1.8% needed intubation. CT scans revealed that the most frequent lung involvement patterns were mixed patterns and consolidation, with bilateral involvement being the most common. The mean CT score was calculated at 3 ± 4. Abnormal CT findings were associated with a poorer prognosis, and correlations were observed between specific CT findings and clinical manifestations.
Chest CT manifestations offer valuable insights for assessing pediatric patients with COVID-19, especially in severe cases and those with pre-existing health conditions. Integrating clinical evaluations with radiological scoring systems facilitates early identification of disease severity.
新冠病毒病已演变成一场影响所有年龄段人群的全球大流行疾病。该疾病可导致严重并发症甚至死亡，尤其是因肺部受累所致。与普遍看法相反，儿童感染新冠病毒病也可能出现严重并发症。迄今为止，针对新冠病毒病儿科患者肺部表现的研究有限。本研究旨在调查伊朗确诊感染新冠病毒病儿童的影像学模式（CT扫描）。
这项回顾性研究分析了2020年3月至2020年9月在德黑兰住院的新冠病毒病儿童的数据。收集的信息包括人口统计学细节（性别和年龄）、既往病史、临床表现、入院时生命体征、实验室检查结果以及影像学结果，包括CT扫描和胸部X线检查。
共纳入252例患者，平均年龄为71.2±59.42个月；58.3%为男性。发热是最常见的症状，67.4%的病例出现该症状。最常见的基础疾病是肿瘤性疾病，85%的患者患有该疾病。值得注意的是，52%的患者需要入住重症监护病房，1.8%的患者需要插管。CT扫描显示，最常见的肺部受累模式是混合模式和实变，双侧受累最为常见。平均CT评分为3±4。CT异常表现与预后较差相关，且特定CT表现与临床表现之间存在相关性。
胸部CT表现为评估新冠病毒病儿科患者提供了有价值的见解，尤其是在重症病例和已有健康问题的患者中。将临床评估与放射学评分系统相结合有助于早期识别疾病严重程度。
