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**儿童**:<18 岁,**实验室确诊** COVID-19 住院率及特征——COVID-NET,14 个州,2020 年 3 月 1 日-7 月 25 日。

Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1-July 25, 2020.

出版信息

MMWR Morb Mortal Wkly Rep. 2020 Aug 14;69(32):1081-1088. doi: 10.15585/mmwr.mm6932e3.

Abstract

Most reported cases of coronavirus disease 2019 (COVID-19) in children aged <18 years appear to be asymptomatic or mild (1). Less is known about severe COVID-19 illness requiring hospitalization in children. During March 1-July 25, 2020, 576 pediatric COVID-19 cases were reported to the COVID-19-Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system that collects data on laboratory-confirmed COVID-19-associated hospitalizations in 14 states (2,3). Based on these data, the cumulative COVID-19-associated hospitalization rate among children aged <18 years during March 1-July 25, 2020, was 8.0 per 100,000 population, with the highest rate among children aged <2 years (24.8). During March 21-July 25, weekly hospitalization rates steadily increased among children (from 0.1 to 0.4 per 100,000, with a weekly high of 0.7 per 100,000). Overall, Hispanic or Latino (Hispanic) and non-Hispanic black (black) children had higher cumulative rates of COVID-19-associated hospitalizations (16.4 and 10.5 per 100,000, respectively) than did non-Hispanic white (white) children (2.1). Among 208 (36.1%) hospitalized children with complete medical chart reviews, 69 (33.2%) were admitted to an intensive care unit (ICU); 12 of 207 (5.8%) required invasive mechanical ventilation, and one patient died during hospitalization. Although the cumulative rate of pediatric COVID-19-associated hospitalization remains low (8.0 per 100,000 population) compared with that among adults (164.5),* weekly rates increased during the surveillance period, and one in three hospitalized children were admitted to the ICU, similar to the proportion among adults. Continued tracking of SARS-CoV-2 infections among children is important to characterize morbidity and mortality. Reinforcement of prevention efforts is essential in congregate settings that serve children, including childcare centers and schools.

摘要

大多数报告的 18 岁以下儿童的 2019 年冠状病毒病(COVID-19)病例似乎为无症状或轻症(1)。对于需要住院治疗的儿童严重 COVID-19 疾病则知之甚少。在 2020 年 3 月 1 日至 7 月 25 日期间,COVID-19 相关住院监测网络(COVID-NET)报告了 576 例儿科 COVID-19 病例,该监测网络是一个基于人群的监测系统,收集了 14 个州与实验室确诊 COVID-19 相关的住院病例数据(2,3)。根据这些数据,2020 年 3 月 1 日至 7 月 25 日期间,年龄<18 岁儿童的 COVID-19 相关住院率累积为每 10 万人 8.0,年龄<2 岁的儿童中该比例最高(24.8)。在 2020 年 3 月 21 日至 7 月 25 日期间,儿童每周住院率稳步上升(从每 10 万人 0.1 例增至 0.4 例,最高为每 10 万人 0.7 例)。总体而言,西班牙裔或拉丁裔(西班牙语裔)和非西班牙裔黑人(黑人)儿童的 COVID-19 相关住院率(分别为每 10 万人 16.4 和 10.5)高于非西班牙裔白人(白人)儿童(每 10 万人 2.1)。在 208 例(36.1%)进行了完整病历回顾的住院儿童中,有 69 例(33.2%)被收入重症监护病房(ICU);207 例中 12 例(5.8%)需要有创机械通气,1 例患者在住院期间死亡。尽管与成年人(164.5)相比,儿科 COVID-19 相关住院率仍较低(每 10 万人 8.0)*,但在监测期间每周住院率有所增加,三分之一的住院儿童被收入 ICU,与成年人的比例相似。持续监测儿童的 SARS-CoV-2 感染对于确定发病率和死亡率很重要。加强针对儿童服务的聚集场所(包括日托中心和学校)的预防措施至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95b1/7440125/b20b3861c513/mm6932e3-F1.jpg

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