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干燥综合征、职业表现与生活质量。

Sjögren's disease, occupational performance and quality of life.

作者信息

Carneiro Cintra Beatriz, Marzola Mateus Maia, Dakuzaku Carretta Regina Yoneko, Reis Oliveira Fabíola, Melani Rocha Eduardo

机构信息

University of São Paulo, Ribeirão Preto, SP, Brazil.

出版信息

Br J Occup Ther. 2025 Mar;88(3):177-184. doi: 10.1177/03080226241284727. Epub 2024 Sep 30.

Abstract

INTRODUCTION

Sjögren's disease is an autoimmune disease with dry eyes and mouth and chronic pain, more frequent in middle-aged women. The aim of this study is to understand the impact of Sjögren's disease on quality of life and occupational health.

METHOD

Quantitative and qualitative comparative study, with 20 Sjögren's disease and 25 healthy controls. Questionnaires and interviews were applied to assess occupational performance, quality of life, mood disorders, and sleep.

RESULTS

The combined major diagnostic parameters for Sjögren's disease (focus score and anti-SSA/Ro positivity) were present in 85% of the Sjögren's disease group. There was a correlation between the sicca symptom measured by the European League Against Rheumatism Sjögren's Syndrome Patient Reported Index (ESSPRI), anxiety, and depression measured by the Hospital Anxiety and Depression Scale (HADS;  = 0.56;  = 0.009), as well as fatigue measured by the Profile of fatigue and discomfort questionnaire (PROFAD) ( = 0.78;  < 0.0001). Sjögren's disease patients reported a loss of physical abilities, sleep disturbance, change in mood, social and occupational participation, and lower quality of life.

CONCLUSIONS

Sjögren's disease patients have poorer quality of life, loss of competencies, and sleep disturbances compared to controls. Novel strategies are necessary to improve occupational health in SjD.

摘要

引言

干燥综合征是一种自身免疫性疾病,表现为眼睛和口腔干燥以及慢性疼痛,在中年女性中更为常见。本研究的目的是了解干燥综合征对生活质量和职业健康的影响。

方法

采用定量和定性比较研究,纳入20例干燥综合征患者和25例健康对照。应用问卷和访谈来评估职业表现、生活质量、情绪障碍和睡眠情况。

结果

85%的干燥综合征组患者存在干燥综合征的综合主要诊断参数(焦点评分和抗SSA/Ro阳性)。欧洲抗风湿病联盟干燥综合征患者报告指数(ESSPRI)测量的干燥症状与医院焦虑抑郁量表(HADS)测量的焦虑和抑郁之间存在相关性(r = 0.56;P = 0.009),以及疲劳和不适问卷(PROFAD)测量的疲劳之间也存在相关性(r = 0.78;P < 0.0001)。干燥综合征患者报告存在身体能力丧失、睡眠障碍、情绪变化、社会和职业参与度下降以及生活质量降低。

结论

与对照组相比,干燥综合征患者的生活质量较差,能力丧失,且存在睡眠障碍。需要新的策略来改善干燥综合征患者的职业健康。

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