Pashko Mykhailo O, Pashkov Kiril V, Granat Dmitriy S, Yagupolskii Yurii L, Ryabukhin Serhiy V, Volochnyuk Dmytro M
Enamine Ltd 78 Winston Churchill str. 02094 Kyiv Ukraine
Institute of Organic Chemistry, National Academy of Sciences of Ukraine 5 Akademik Kuhar str. 02660 Kyiv Ukraine.
RSC Adv. 2025 May 8;15(19):15116-15120. doi: 10.1039/d5ra01538c. eCollection 2025 May 6.
A promising reagent for introducing the methyl thionoester function into organic molecules through a straightforward synthetic sequence based on common magnesium organics is proposed. A scalable procedure for its production is elaborated. The potential of the reaction, along with its advantages/simplicity, convenience, and effectiveness, is demonstrated and discussed.
本文提出了一种有前景的试剂，可通过基于常见有机镁化合物的直接合成序列将甲硫代酯官能团引入有机分子中。详细阐述了其可扩展的制备方法。论证并讨论了该反应的潜力及其优势，包括简单性、便利性和有效性。
