Gao Hang, Xiao Jinzhi, Zhang Qi, Man Hutianlin, Tang Xingyi, Wang Zhouyuan, Fang Rendong, Jiang Sha
Joint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Kunming Hemeihua Feed Limited Company, Kunming, China.
Front Vet Sci. 2025 Apr 24;12:1584627. doi: 10.3389/fvets.2025.1584627. eCollection 2025.
The aim of this study was to investigate effect of (BS), yeast cell wall (YCW), and their combination on intestinal and bone development and egg production of young hens. A total of 160, one-day-old Hy-Line Sonia chicks were randomly allocated into 4 treatments of 8 replicate cages of 5 birds each. Treatments were arranged in a 2 (0 and 0.5 g/kg of BS) × 2 (0 and 2 g/kg of YCW) factorial arrangement for a duration of 170-d as follows: (1) regular diet (Control group); (2) the regular diet plus 0.5 g BS/kg (BS group); (3) the regular diet plus 2 g YCW/kg (YCW group); and (4) the regular diet plus 0.5 g BS/kg and 2 g YCW/kg (BS + YCW group). One bird from each of the 8 replicate cages per treatment were randomly taken for sampling at d 110 and 170, respectively. Results indicated that there were different effects of BS and YCW on bird organ development and innate immune. YCW supplementation increased thymus index and serum concentrations of IgM of hens ( < 0.05). In addition, an interaction was observed between YCW diet and age on serum IL-6 concentrations ( < 0.05), mainly because YCW birds had the highest serum IL-6 concentration at d 110. Dietary supplementation with BS reduced the crypt depth in the duodenum and jejunum with an increased ratio of villus height to crypt depth ( < 0.05) in the duodenum, jejunum, and ileum. However, a YCW × age interaction on the jejunal villus height existed, mainly because non-YCW diet had the lowest jejunal villus height at d 170 ( < 0.05). Both BS and YCW enhanced egg weight, eggshell thickness and yolk color ( < 0.05), while YCW improved albumen height and Haugh unit ( < 0.05). There was no treatment effect on measured bone parameters except that YCW birds had lager tibial diameter ( < 0.05) at d 170. The results indicate that dietary BS and/or YCW improve the intestinal and bone development and immune status of young hens, which may contribute to the increased egg quality during the early sexual maturity stage.
本研究旨在探讨丁酸梭菌（BS）、酵母细胞壁（YCW）及其组合对雏鸡肠道和骨骼发育以及产蛋性能的影响。总共160只1日龄海兰索尼亚雏鸡被随机分为4个处理组，每个处理组有8个重复笼，每个笼中有5只鸡。处理组按2（0和0.5 g/kg BS）×2（0和2 g/kg YCW）析因设计安排，为期170天，如下：（1）常规日粮（对照组）；（2）常规日粮加0.5 g BS/kg（BS组）；（3）常规日粮加2 g YCW/kg（YCW组）；（4）常规日粮加0.5 g BS/kg和2 g YCW/kg（BS+YCW组）。在第110天和170天，分别从每个处理组的8个重复笼中随机选取1只鸡进行采样。结果表明，BS和YCW对鸡的器官发育和先天免疫有不同影响。添加YCW可提高母鸡的胸腺指数和血清IgM浓度（P<0.05）。此外，观察到YCW日粮与年龄对血清IL-6浓度存在交互作用（P<0.05），主要是因为在第110天，添加YCW的鸡血清IL-6浓度最高。日粮添加BS可降低十二指肠和空肠的隐窝深度，增加十二指肠、空肠和回肠绒毛高度与隐窝深度的比值（P<0.05）。然而，在空肠绒毛高度上存在YCW×年龄交互作用，主要是因为在第170天，未添加YCW的日粮组空肠绒毛高度最低（P<0.05）。BS和YCW均提高了蛋重、蛋壳厚度和蛋黄颜色（P<0.05），而YCW改善了蛋白高度和哈氏单位（P<0.05）。除了在第170天添加YCW的鸡胫骨直径更大（P<0.05）外，各处理组对所测骨骼参数均无影响。结果表明，日粮中添加BS和/或YCW可改善雏鸡的肠道和骨骼发育以及免疫状态，这可能有助于在性成熟早期提高蛋品质。
