Pennington Zach, Martini Michael L, Mikula Anthony L, Astudillo Potes Maria, Hamouda Abdelrahman M, Lakomkin Nikita, Sebastian Arjun, Freedman Brett A, Nassr Ahmad N, Fogelson Jeremy L, Elder Benjamin D
1Departments of Neurologic Surgery and.
2Orthopaedic Surgery, Mayo Clinic, Rochester, Minnesota.
J Neurosurg Spine. 2025 May 9;43(1):9-18. doi: 10.3171/2025.2.SPINE24706. Print 2025 Jul 1.
Pelvic incidence (PI) is a key parameter of sagittal alignment. While conventionally held to be fixed, increasing evidence suggests PI may be variable. This study aimed to identify predictors of change in PI with patient position and to assess the association of preoperative radiographic characteristics and intraoperative maneuvers with postoperative PI.
Patients who underwent thoracolumbosacral fusion were identified, and data were gathered on preoperative spinopelvic parameters, patient demographic characteristics, and operative details. Preoperative spinopelvic parameters were measured on upright, supine, and prone radiographs. Univariable comparisons of PI between the different patient positions were performed. Multivariable analysis was performed to identify variables independently correlated with PI on 6-week postoperative radiographs. Change in PI was defined as ≥ 5° change between positions.
In total, 138 patients were identified (mean ± SD age 66.0 ± 8.7 years; 38.4% male). Statistically significant differences in PI were noted between preoperative standing and supine (mean -3.2° ± 4.2°, p < 0.001), preoperative supine and prone (3.5° ± 4.7°, p < 0.001), preoperative and 6-week postoperative standing (1.5° ± 6.2°, p = 0.01), and immediate and 6-week upright (1.1° ± 3.9°, p = 0.007) radiographs. Univariable comparisons showed PI decrease from standing to supine was predicted only by weight (87.0 ± 15.0 vs 81.1 ± 19.3 kg, p = 0.04); there were no significant predictors of increase in PI from standing to prone. Increase in PI from preoperative to 6-week standing radiographs was predicted by lower preoperative PI class (p < 0.001), L5/S1 interbody placement (74.4% vs 52.0%, p = 0.02), and change in PI from preoperative standing to supine (12.8% vs 39.8%, p = 0.002) and from standing to prone (51.3% vs 13.3%, p < 0.001). Multivariable analysis showed that 6-week postoperative PI was associated with only preoperative supine PI (B = 0.293, 95% CI 0.10-0.48, p = 0.003) and prone PI (B = 0.647, 95% CI 0.44-0.85, p < 0.001).
There are position-dependent changes in PI among patients without prior pelvic fixation. Statistically significant changes in PI are seen even after pelvic fixation with a single S2-alar-iliac screw bilaterally. Postoperative PI was best predicted by preoperative PI on supine and prone radiographs rather than upright radiographs, suggesting that preoperative prone and supine radiographs may provide surgeons with the best information for achieving PI-lumbar lordosis mismatch < 10°.
骨盆入射角(PI)是矢状面排列的关键参数。传统观点认为其固定不变,但越来越多的证据表明PI可能存在变化。本研究旨在确定PI随患者体位变化的预测因素,并评估术前影像学特征和术中操作与术后PI的相关性。
纳入接受胸腰段骶椎融合术的患者,收集术前脊柱骨盆参数、患者人口统计学特征及手术细节数据。术前脊柱骨盆参数在站立位、仰卧位和俯卧位X线片上测量。对不同患者体位的PI进行单变量比较。进行多变量分析以确定与术后6周X线片上PI独立相关的变量。PI的变化定义为不同体位间变化≥5°。
共纳入138例患者(平均年龄±标准差66.0±8.7岁;男性占38.4%)。术前站立位与仰卧位PI存在统计学显著差异(平均-3.2°±4.2°,p<0.001),术前仰卧位与俯卧位(3.5°±4.7°,p<0.001),术前与术后6周站立位(1.5°±6.2°,p = 0.01),以及即刻与6周站立位(1.1°±3.9°,p = 0.007)X线片。单变量比较显示,仅体重可预测站立位到仰卧位PI降低(87.0±15.0 vs 81.1±19.3 kg,p = 0.04);无显著因素可预测站立位到俯卧位PI增加。术前到术后6周站立位X线片PI增加可由术前较低的PI分级(p<0.001)、L5/S1椎间融合器置入(74.4% vs 52.0%,p = 0.02),以及术前站立位到仰卧位PI变化(12.8% vs 39.8%,p = 0.002)和站立位到俯卧位PI变化(51.3% vs 13.3%,p<0.001)预测。多变量分析显示,术后6周PI仅与术前仰卧位PI(B = 0.293,95%CI 0.10 - 0.48,p = 0.003)和俯卧位PI(B = 0.647,95%CI 0.44 - 0.85,p<0.001)相关。
在未行骨盆固定的患者中,PI存在体位依赖性变化。即使双侧单枚S2-翼-髂螺钉骨盆固定后,PI仍有统计学显著变化。术后PI最好由术前仰卧位和俯卧位X线片上的PI预测,而非站立位X线片,这表明术前俯卧位和仰卧位X线片可为外科医生提供实现PI-腰椎前凸失配<10°的最佳信息。