Lofuta Olenga Vuvu Pierre, Klass Malgorzata, Pauwen Nathalie, Kipula Augustin Mboko, van de Borne Philippe, van Muylem Alain, Perez-Bogerd Silvia, Deboeck Gael
Cardiopulmonary Rehabilitation Unit, Physical Medicine and Rehabilitation Department, University Clinics of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Research Unit in Rehabilitation Sciences, Faculty of Human Movement Sciences, Université Libre de Bruxelles, Brussels, Belgium.
Physiol Rep. 2025 May;13(9):e70368. doi: 10.14814/phy2.70368.
Exposure to charcoal biomass (CB) pollutants affects the cardiorespiratory system. We assessed cardiopulmonary responses (CPR) to exercise in charcoal producers (CPs) compared to farmers and evaluated the prevalence of exercise-induced bronchoconstriction (EIB). Forty-five CPs and 36 farmers, healthy males aged 23-39, completed a 15-m Incremental Shuttle Walk and Run Test (15-m ISWRT). Air quality index (AQI) and CO intoxication were measured, CPR was assessed through heart rate (HR), blood pressures (SBP, DBP), and spirometry at rest, peak exercise, and during recovery at 5 and 15 min. Aerobic capacity (VO max) was estimated from the distance covered during the 15-m ISWRT, and EIB was defined as a >10% decrease in FEV1 from baseline values. AQI was worse in charcoal workplaces, and CPs had higher CO intoxication than farmers (p < 0.0001). Both groups reached maximal exercise %HRmax: 84 (82-89) versus 84 (80-89), p = 0.37 and showed similar predicted VO max 36.2 (31.1-43.1) versus 38.9 (32.2-43.7) mL/kg/min, p = 0.60. However, after ISWRT, CPs had lower FEV1 than farmers (2.9 ± 0.6 vs. 3.3 ± 0.6 L, p < 0.003) and slower recovery. EIB prevalence was higher in CPs (60.0% vs. 27.8%, p = 0.006). Chronic exposure to CB increases EIB in healthy CPs, suggesting heightened airway hyperreactivity.
接触木炭生物质（CB）污染物会影响心肺系统。我们评估了木炭生产者（CPs）与农民相比在运动时的心肺反应（CPR），并评估了运动诱发支气管收缩（EIB）的患病率。45名CPs和36名年龄在23 - 39岁的健康男性农民完成了15米递增往返跑和跑步测试（15 - m ISWRT）。测量了空气质量指数（AQI）和一氧化碳中毒情况，通过心率（HR）、血压（SBP、DBP）以及在静息、运动峰值和恢复5分钟及15分钟时的肺活量测定来评估CPR。根据15 - m ISWRT期间所覆盖的距离估算有氧能力（VO max），EIB定义为第一秒用力呼气容积（FEV1）较基线值下降>10%。木炭工作场所的AQI更差，CPs的一氧化碳中毒程度高于农民（p < 0.0001）。两组均达到最大运动心率百分比（%HRmax）：84（82 - 89）与84（80 - 89），p = 0.37，且预测的VO max相似，分别为36.2（31.1 - 43.1）与38.9（32.2 - 43.7）mL/kg/min，p = 0.60。然而，在ISWRT后，CPs的FEV1低于农民（2.9 ± 0.6与3.3 ± 0.6 L，p < 0.003），且恢复较慢。CPs中EIB的患病率更高（60.0%对27.8%，p = 0.006）。长期接触CB会增加健康CPs中的EIB，提示气道高反应性增强。
