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[儿童风湿性肩关节]

[Rheumatic shoulder joints in childhood].

作者信息

Windschall Daniel, Bork Hartmut, Gohar Faekah, Maier Anna

机构信息

Klinik für Kinder- und Jugendrheumatologie, Rheumatologisches Kompetenzzentrum Nordwestdeutschland St. Josef-Stift-Sendenhorst, Westtor 7, 48324, Sendenhorst, Deutschland.

Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, Halle, Deutschland.

出版信息

Z Rheumatol. 2025 Jun;84(5):373-380. doi: 10.1007/s00393-025-01654-8. Epub 2025 May 9.

DOI:10.1007/s00393-025-01654-8
PMID:40346183
Abstract

Although the knee joint in children and adolescents is most frequently affected in cases of juvenile idiopathic arthritis (JIA), shoulder joint arthritis is only present in a small proportion of JIA patients at disease onset. Shoulder joint involvement is more frequently seen in polyarthritis or chronic JIA, which if not considered and left untreated can lead to substantial joint immobility and with a destructive course. In addition to the clinical examination, imaging methods help to verify an early involvement of the shoulder joint and imaging can also provide important information in a treat to target concept. The treatment of pediatric omarthritis is very often guided by the treatment algorithm for the appropriate JIA category. In this respect, in addition to local steroid injections, medications such as methotrexate, biologicals and also Janus kinase (JAK) inhibitors are used. In addition to the pharmacotherapy, physiotherapy also plays an important role.

摘要

尽管在幼年特发性关节炎(JIA)病例中,儿童和青少年的膝关节最常受累,但在疾病发作时,只有一小部分JIA患者存在肩关节关节炎。肩关节受累在多关节炎或慢性JIA中更常见,如果不加以考虑和治疗,可能会导致严重的关节活动障碍,并伴有破坏性病程。除了临床检查外,影像学方法有助于证实肩关节的早期受累,并且影像学在目标治疗理念中也能提供重要信息。小儿多关节炎的治疗通常由适用于相应JIA类别的治疗算法指导。在这方面,除了局部注射类固醇外,还使用甲氨蝶呤、生物制剂以及 Janus激酶(JAK)抑制剂等药物。除了药物治疗外,物理治疗也起着重要作用。

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本文引用的文献

1
Treatment of non-systemic juvenile idiopathic arthritis.非系统性幼年特发性关节炎的治疗。
Nat Rev Rheumatol. 2024 Mar;20(3):170-181. doi: 10.1038/s41584-024-01079-8. Epub 2024 Feb 6.
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Patterns of clinical joint inflammation in juvenile idiopathic arthritis.幼年特发性关节炎的临床关节炎症模式。
RMD Open. 2023 Mar;9(1). doi: 10.1136/rmdopen-2022-002941.
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Update of evidence- and consensus-based guidelines for the treatment of juvenile idiopathic arthritis (JIA) by the German Society of Pediatric and Juvenile Rheumatic Diseases (GKJR): New perspectives on interdisciplinary care.
德国儿科和青少年风湿学会(GKJR)更新了针对青少年特发性关节炎(JIA)治疗的循证和共识指南:跨学科治疗的新视角。
Clin Immunol. 2022 Dec;245:109143. doi: 10.1016/j.clim.2022.109143. Epub 2022 Sep 30.
4
Juvenile idiopathic arthritis: from aetiopathogenesis to therapeutic approaches.幼年特发性关节炎:从发病机制到治疗方法。
Pediatr Rheumatol Online J. 2021 Aug 23;19(1):135. doi: 10.1186/s12969-021-00629-8.
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Ultrasound imaging in paediatric rheumatology.儿科风湿病学中的超声成像。
Best Pract Res Clin Rheumatol. 2020 Dec;34(6):101570. doi: 10.1016/j.berh.2020.101570. Epub 2020 Aug 25.
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Shoulder arthroplasty for juvenile idiopathic arthritis.青少年特发性关节炎的肩关节置换术。
J Orthop Surg (Hong Kong). 2020 Jan-Apr;28(1):2309499019890615. doi: 10.1177/2309499019890615.
7
Depression And Anxiety In Patients With Juvenile Idiopathic Arthritis: Current Insights And Impact On Quality Of Life, A Systematic Review.青少年特发性关节炎患者的抑郁和焦虑:当前见解及其对生活质量的影响,一项系统综述
Open Access Rheumatol. 2019 Nov 1;11:237-252. doi: 10.2147/OARRR.S174408. eCollection 2019.
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The role of imaging in juvenile idiopathic arthritis.影像学在幼年特发性关节炎中的作用。
Expert Rev Clin Immunol. 2018 Aug;14(8):681-694. doi: 10.1080/1744666X.2018.1496019. Epub 2018 Jul 20.
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Baseline ultrasound examination as possible predictor of relapse in patients affected by juvenile idiopathic arthritis (JIA).基线超声检查可能是预测幼年特发性关节炎(JIA)患者复发的指标。
Ann Rheum Dis. 2018 Oct;77(10):1426-1431. doi: 10.1136/annrheumdis-2017-211696. Epub 2018 Feb 6.
10
Arthrosonographic Reference Values of the Shoulder Joint in Healthy Children and Adolescents: A Cross-Sectional Multicentre Ultrasound Study.健康儿童和青少年肩关节的关节超声参考值:一项横断面多中心超声研究
Klin Padiatr. 2017 Sep;229(5):293-301. doi: 10.1055/s-0043-111596. Epub 2017 Aug 24.