Suszek Dorota, Popławska Magdalena, Prośniak Jakub, Siemieniec Katarzyna, Przeniosło Karolina, Wallach Weronika, Żybowska-Męczyńska Monika, Ostrowicz Klaudia, Rzewuska-Fijałkowska Anna, Targońska-Stępniak Bożena
Department of Rheumatology and Connective Tissue Diseases, Medical University, Lublin, Poland.
Department of Rheumatology and Connective Tissue Diseases, St. Jaczewskiego 8, Lublin, 20-954, Poland.
Rheumatol Int. 2025 May 10;45(6):139. doi: 10.1007/s00296-025-05894-4.
Systemic lupus erythematosus (SLE) patients have a significantly increased risk of developing cardiovascular disease (CVD). Despite the implementation of preventive measures and treatment of lipid disorders, as well as reduced use of glucocorticoids, CVD remains one of the leading causes of death in this patient group. It is crucial to develop an appropriate CVD risk assessment strategy that considers the distinctive characteristics of this patient population. This paper provides a comprehensive analysis of the methods used to assess CVD risk in SLE patients. It also presents effective strategies for the reduction of the effects of traditional and non-traditional risk factors for atherosclerosis.
系统性红斑狼疮(SLE)患者患心血管疾病(CVD)的风险显著增加。尽管采取了预防措施和对脂质紊乱进行治疗,以及减少了糖皮质激素的使用,但CVD仍然是该患者群体的主要死因之一。制定一种考虑到该患者群体独特特征的适当的CVD风险评估策略至关重要。本文对用于评估SLE患者CVD风险的方法进行了全面分析。它还提出了减少动脉粥样硬化传统和非传统风险因素影响的有效策略。