Karaoglu Turan, Tanriverdi Ozgur
Faculty of Medicine, Department of Medical Oncology, Mugla Sıtkı Koçman University, Kötekli Mh. Marmaris Yolu Bulvarı No: 55 Menteşe, 48000, Mugla, Turkey.
Appl Psychophysiol Biofeedback. 2025 May 10. doi: 10.1007/s10484-025-09712-2.
Music and medicine interventions are recognised for their effects on emotional regulation and stress reduction. However, limited research exists on how these interventions affect anxiety based on personality types, particularly in breast cancer patients undergoing chemotherapy. This study aimed to evaluate the effects of music and medicine interventions on anxiety levels according to personality types in women with breast cancer receiving adjuvant chemotherapy. In a controlled, cross-sectional case-control study, 120 women were randomly assigned to two groups: an intervention group (music and medicine + chemotherapy) and a control group (chemotherapy only). The music playlist included classical, folk, and pop genres, and participants' anxiety levels were measured using the State-Trait Anxiety Inventory. Personality types were determined post-treatment using the Eysenck Personality Questionnaire - Revised Short Form. Serum C-reactive protein levels, blood pressure, and heart rate were also measured. Significant reductions were observed in anxiety levels, systolic blood pressure, heart rate, and serum C-reactive protein levels in the music intervention group compared to the control group. Neurotic individuals showed the most substantial improvement in anxiety, with reductions in systolic blood pressure and heart rate. Multivariate analysis revealed that both neurotic personality type and the music intervention were significant predictors of anxiety reduction. Music and medicine interventions provide notable benefits in reducing anxiety, particularly in neurotic individuals. Personalised music therapy based on personality types could enhance the quality of life for breast cancer patients undergoing chemotherapy. While this study focuses on the immediate effects of MMI during the first chemotherapy session, future research should explore the long-term impacts to better understand the sustained efficacy of such interventions in managing anxiety across multiple treatment cycles.
音乐和药物干预因其对情绪调节和减轻压力的作用而得到认可。然而，关于这些干预如何根据人格类型影响焦虑的研究有限，尤其是在接受化疗的乳腺癌患者中。本研究旨在评估音乐和药物干预对接受辅助化疗的乳腺癌女性患者根据人格类型的焦虑水平的影响。在一项对照的横断面病例对照研究中，120名女性被随机分为两组：干预组（音乐和药物+化疗）和对照组（仅化疗）。音乐播放列表包括古典、民间和流行音乐类型，参与者的焦虑水平使用状态-特质焦虑量表进行测量。治疗后使用艾森克人格问卷修订简式确定人格类型。还测量了血清C反应蛋白水平、血压和心率。与对照组相比，音乐干预组的焦虑水平、收缩压、心率和血清C反应蛋白水平显著降低。神经质个体在焦虑方面表现出最大的改善，收缩压和心率降低。多变量分析显示，神经质人格类型和音乐干预都是焦虑减轻的显著预测因素。音乐和药物干预在减轻焦虑方面提供了显著益处，尤其是在神经质个体中。基于人格类型的个性化音乐疗法可以提高接受化疗的乳腺癌患者的生活质量。虽然本研究关注MMI在第一次化疗期间的即时效果，但未来的研究应探索长期影响，以更好地了解此类干预在多个治疗周期中管理焦虑的持续疗效。
