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台湾男同性恋者的暴露前预防参与情况:行为健康视角

Pre-exposure prophylaxis engagement among sexual minority men in Taiwan: a behavioral health perspective.

作者信息

Mayo Daniel, Huang Poyao

机构信息

Global Health Program, National Taiwan University College of Public Health, Taipei, Taiwan.

Department of Behavioral and Social Sciences, Brown University School of Public Health, Box G-S121-3, Providence, RI, 02912, US.

出版信息

J Behav Med. 2025 May 10. doi: 10.1007/s10865-025-00572-z.

DOI:10.1007/s10865-025-00572-z
PMID:40348939
Abstract

In Taiwan, sexual minority men (SMM) account for a significant portion of new HIV cases, highlighting the need for effective prevention measures. However, pre-exposure prophylaxis (PrEP) use remains limited, necessitating a comprehensive examination of barriers. This study examined PrEP engagement and its predictors among 284 SMM in Taiwan. Participants were categorized into five stages, based on the Transtheoretical Model of Health Behavior Change, reflecting distinct levels of PrEP engagement. Ordinal logistic regression, informed by the Behavioral Model of Health Service Use, identified factors associated with being positioned at higher stages of the cascade. Significant predictors of PrEP engagement included predisposing (i.e., relationship status), enabling (i.e., PrEP knowledge, community connectedness), and need factors (i.e., number of sexual partners, chemsex). Findings highlight the need for further research on education, relationship dynamics, and sexual risk behaviors to inform tailored interventions that enhance PrEP engagement among SMM in Taiwan and the broader Asia region.

摘要

在台湾,性少数男性(SMM)占新增艾滋病毒病例的很大一部分,这凸显了采取有效预防措施的必要性。然而,暴露前预防(PrEP)的使用仍然有限,因此有必要对相关障碍进行全面审视。本研究调查了台湾284名性少数男性的PrEP参与情况及其预测因素。根据健康行为改变的跨理论模型,参与者被分为五个阶段,反映了不同程度的PrEP参与情况。基于健康服务利用行为模型进行的有序逻辑回归,确定了与处于级联较高阶段相关的因素。PrEP参与的显著预测因素包括易患因素(即恋爱状况)、促成因素(即PrEP知识、社区联系)和需求因素(即性伴侣数量、化学性行为)。研究结果强调,需要进一步研究教育、恋爱动态和性风险行为,以便为量身定制的干预措施提供信息,从而提高台湾及更广泛亚洲地区性少数男性对PrEP的参与度。

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本文引用的文献

1
Pre-Exposure Prophylaxis Care Continuum for HIV Risk Populations: An Umbrella Review of Systematic Reviews and Meta-Analyses.HIV 风险人群的暴露前预防护理连续体:系统评价和荟萃分析的伞式综述。
AIDS Patient Care STDS. 2023 Dec;37(12):583-615. doi: 10.1089/apc.2023.0158. Epub 2023 Nov 21.
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Adapting Effective mHealth Interventions to Improve Uptake and Adherence to HIV Pre-Exposure Prophylaxis Among Thai Young Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial.调整有效的移动健康干预措施以提高泰国男男性行为者对艾滋病病毒暴露前预防的接受度和依从性:一项随机对照试验方案
JMIR Res Protoc. 2023 Sep 4;12:e46435. doi: 10.2196/46435.
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HIV Risk Perception, Willingness to Use PrEP, and PrEP Uptake Among Young Men who have Sex with Men in Washington, DC.
华盛顿特区男男性行为者的 HIV 风险感知、使用 PrEP 的意愿和 PrEP 接受情况。
AIDS Behav. 2023 Sep;27(9):2844-2854. doi: 10.1007/s10461-023-04008-0. Epub 2023 Feb 20.
4
Engaging Latino sexual minority men in PrEP and behavioral health care: multilevel barriers, facilitators, and potential implementation strategies.让拉丁裔性少数男性参与 PrEP 和行为保健服务:多层次障碍、促进因素和潜在实施策略。
J Behav Med. 2023 Aug;46(4):655-667. doi: 10.1007/s10865-022-00371-w. Epub 2022 Dec 6.
5
Daily and on-demand HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil (ANRS PREVENIR): a prospective observational cohort study.每日按需服用恩曲他滨和替诺福韦地索普西(ANRS PREVENIR)进行艾滋病毒暴露前预防:一项前瞻性观察队列研究。
Lancet HIV. 2022 Aug;9(8):e554-e562. doi: 10.1016/S2352-3018(22)00133-3. Epub 2022 Jun 27.
6
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AIDS Behav. 2022 Apr;26(4):1211-1221. doi: 10.1007/s10461-021-03476-6. Epub 2021 Sep 21.
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Drug Alcohol Depend. 2021 Sep 1;226:108875. doi: 10.1016/j.drugalcdep.2021.108875. Epub 2021 Jun 25.
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