Iwamuro Masaya, Kikuchi Satoru, Kuroda Shinji, Tanaka Takehiro, Otsuka Motoyuki
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, JPN.
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, JPN.
Cureus. 2025 Apr 10;17(4):e82046. doi: 10.7759/cureus.82046. eCollection 2025 Apr.
Gastrointestinal stromal tumors (GISTs) are often detected incidentally during esophagogastroduodenoscopy. Although surgical resection is the standard treatment for GISTs, patients with significant comorbidities may not be eligible for surgery and are managed conservatively. Herein, we report two cases of gastric GISTs that were initially observed during the management of other comorbidities but subsequently became enlarged, resulting in gastrointestinal bleeding. These cases highlight the potential risks of tumor progression and bleeding in patients undergoing conservative management.
胃肠道间质瘤(GISTs)常在食管胃十二指肠镜检查时偶然发现。尽管手术切除是GISTs的标准治疗方法,但有严重合并症的患者可能不符合手术条件,需进行保守治疗。在此,我们报告两例胃GISTs病例,最初是在治疗其他合并症时发现的,但随后肿瘤增大,导致胃肠道出血。这些病例凸显了接受保守治疗的患者肿瘤进展和出血的潜在风险。