Gonzalez Aguirre Catalina, Gallardo-Navarro Elias, Castillo Magaña Antonio
Oncologic Surgery, Spanish Hospital, Mexico City, MEX.
General Surgery, Spanish Hospital, Mexico City, MEX.
Cureus. 2025 Apr 10;17(4):e81999. doi: 10.7759/cureus.81999. eCollection 2025 Apr.
When a patient is diagnosed with more than one tumor in the same organ or in a different one, there may be multiple primary tumors. We present the case of a patient with an initial diagnosis of undifferentiated pleomorphic sarcoma (UPS) of the posterior region of the neck in whom an extension study was requested after surgery prior to the systemic therapy; tumor activity was identified in the left testicle, and radical orchiectomy was performed with the result of non-Hodgkin lymphoma (NHL) B cells. Multiple primary neoplasms have different histologies and different sites of origin. The interest of the case arises from the clinical presentation in which the patient is being staged due to a previously diagnosed malignant tumor, and a second tumor is detected in the positron emission tomography (PET) scan. Because of the characteristics of the first neoplasm, it is very unlikely that it could correspond to metastasis of the known primary tumor; therefore, it is suspected to be another primary tumor that requires histological confirmation.
当一名患者在同一器官或不同器官被诊断出患有不止一个肿瘤时，可能存在多个原发性肿瘤。我们报告一例患者，最初诊断为颈部后部未分化多形性肉瘤（UPS），术后在进行全身治疗前要求进行进一步检查；在左侧睾丸发现肿瘤活动，遂行根治性睾丸切除术，结果为B细胞非霍奇金淋巴瘤（NHL）。多个原发性肿瘤具有不同的组织学特征和不同的起源部位。该病例的有趣之处在于其临床表现，即患者因先前诊断的恶性肿瘤而进行分期检查时，在正电子发射断层扫描（PET）中发现了第二个肿瘤。由于第一个肿瘤的特征，它极不可能是已知原发性肿瘤的转移；因此，怀疑它是另一个需要组织学确认的原发性肿瘤。
