Reddy Ravikanth
Radiodiagnosis, St. John's Hospital, Bengaluru, IND.
Cureus. 2021 Aug 6;13(8):e16958. doi: 10.7759/cureus.16958. eCollection 2021 Aug.
Malignant fibrous histiocytoma currently known as undifferentiated pleomorphic sarcoma is the commonest soft tissue sarcoma of mesenchymal origin. Undifferentiated pleomorphic sarcoma is commonly located in the extremities, trunk, head and neck in decreasing order of frequency. We report a case of primary undifferentiated pleomorphic sarcoma of the biceps femoris muscle in a 50-year-old male complicated by hemorrhage. Diagnostic workup included ultrasonography, magnetic resonance imaging (MRI), histopathology and positive results on immunohistochemistry especially CD-68. High-grade liposarcoma and rhabdomyosarcoma were regarded as differential diagnoses of undifferentiated pleomorphic sarcoma. Demonstration of spontaneous hemorrhage within the lesion on follow-up ultrasonography done at one month from the time of diagnosis deserves a special mention in this report. Radical excision with tumor-free margins of the biceps femoris and tendon reconstruction was undertaken. MRI at six months follow-up did not reveal tumor recurrence at the site of surgery and CT chest did not reveal metastases.
恶性纤维组织细胞瘤目前称为未分化多形性肉瘤，是间充质来源最常见的软组织肉瘤。未分化多形性肉瘤通常按频率递减顺序位于四肢、躯干、头颈部。我们报告一例50岁男性股二头肌原发性未分化多形性肉瘤并发出血的病例。诊断性检查包括超声检查、磁共振成像（MRI）、组织病理学检查以及免疫组织化学检查（尤其是CD-68）呈阳性结果。高分化脂肪肉瘤和横纹肌肉瘤被视为未分化多形性肉瘤的鉴别诊断。本报告特别提及在诊断后1个月进行的随访超声检查显示病变内有自发性出血。对股二头肌进行了切缘无肿瘤的根治性切除并进行了肌腱重建。术后6个月的MRI检查未显示手术部位有肿瘤复发，胸部CT检查未显示转移。
