Pneumonia is a common cause of morbidity and mortality in the United States and worldwide. It is most commonly caused by a single organism, but co-infection can occur. Nevertheless, there are no or very few reported cases of triple acute co-infection with a virus, a bacterium, and a fungus in an immunocompetent patient without underlying chronic lung disease. Here, we discuss a case in which an otherwise healthy, elderly male exhibited a triple co-infection with coronavirus NL63, or (also known as a cause of Valley fever), and . We discuss the insight this clinical course can provide on future diagnosis and management of pulmonary coinfections.