Bernasconi C, Agostoni A
Ric Clin Lab. 1985;15 Suppl 1:11-25.
A method for studying blood viscosity at low shear rates (from 4 x 10(-2) to 7 x 10(1) sec-1), i.e. in the shear range in which higher is the influence of shear rate on viscosity, was developed. Blood viscosity is expressed by the two regression coefficients of a power regression, according to the function: eta = a . Db where eta is viscosity. D is the shear rate, a and b are the two regression coefficients, which are independent of the shear rate. We found that the regression power was highly significant in a wide hematocrit range. Practically, this work deals with the possibility of application to the blood of the Ostwald formula for pseudoplastic flow behavior. We found significant correlations between the two regression coefficients and hematocrit and plasma viscosity, so correcting by calculation the two regression coefficients for standard hematocrit and standard plasma viscosity. This method is simple and can easily be automatically driven by a computer.
开发了一种研究低剪切速率(从4×10⁻²到7×10¹秒⁻¹)下血液粘度的方法,即在剪切速率对粘度影响较大的剪切范围内进行研究。根据函数η = a·Dᵇ,血液粘度由幂回归的两个回归系数表示,其中η为粘度,D为剪切速率,a和b为两个回归系数,它们与剪切速率无关。我们发现,在较宽的血细胞比容范围内,回归幂具有高度显著性。实际上,这项工作探讨了将奥斯特瓦尔德假塑性流动行为公式应用于血液的可能性。我们发现两个回归系数与血细胞比容和血浆粘度之间存在显著相关性,因此通过计算对标准血细胞比容和标准血浆粘度的两个回归系数进行校正。该方法简单,并且可以很容易地由计算机自动驱动。