Reinhart W H, Danoff S J, Usami S, Chien S
J Lab Clin Med. 1984 Dec;104(6):921-31.
A newly developed capillary viscometer (capillary diameter 496 micron, length 10 cm) was tested and used for measurement of blood viscosity. The determination of pressure drop along the capillary during a constant flow allowed the calculation of the apparent viscosity. By changing the flow rate, the shear rate could be varied from 0.67 to 590 sec-1. A sample of 0.5 ml was sufficient for readings to be made at 10 shear rates in this range. Measurements of distilled water and standard oils were in good agreement with the expected values. Measurements on adult human plasma and umbilical cord blood were compared with simultaneous readings by Couette viscometer. For whole blood at various shear rates, regression analysis between the viscosity obtained from the capillary viscometer and that from the Couette viscometer yielded excellent correlation (r = 0.968, p less than 0.001). This capillary viscometer with high precision for very small samples is useful for various clinical applications.
一种新开发的毛细管粘度计(毛细管直径496微米,长度10厘米)经过测试并用于测量血液粘度。在恒定流量下测定沿毛细管的压降可计算表观粘度。通过改变流速,剪切速率可在0.67至590秒-1之间变化。0.5毫升的样品足以在此范围内的10个剪切速率下进行读数。蒸馏水和标准油的测量结果与预期值吻合良好。将成人血浆和脐带血的测量结果与库埃特粘度计的同步读数进行了比较。对于不同剪切速率下的全血,毛细管粘度计测得的粘度与库埃特粘度计测得的粘度之间的回归分析显示出极好的相关性(r = 0.968,p小于0.001)。这种对非常小的样品具有高精度的毛细管粘度计可用于各种临床应用。