Pernigotti L, Neirotti M, Cappa G, Musso M, Fabris F
Ric Clin Lab. 1985;15 Suppl 1:307-12.
Blood filtration and viscosity were investigated in 32 patients with severe mental deterioration classified on the basis of standard criteria. The group included 17 patients with 'vascular' and 15 with 'cellular' pathogenesis. The results of the study were compared with the data from a large series of 'normal' subjects. Reduced erythrocyte filtration was observed in 70.5% of the patients with vascular pathogenesis and in only 6.6% of those with degenerative conditions. The data on blood viscosity showed less connection between pathological conditions and hemorheological alterations. It is suggested that hemorheological alterations might contribute to the pathogenesis of certain clinical forms of chronic cerebropathy. It is therefore proposed that hemorheological tests should be included among the diagnostic procedures applied to such patients and might also be used in order to establish the appropriate treatment.
依据标准标准，对32例重度精神衰退患者的血液过滤和黏度进行了研究。该组包括17例“血管性”发病机制患者和15例“细胞性”发病机制患者。将研究结果与大量“正常”受试者的数据进行了比较。在70.5%的血管性发病机制患者中观察到红细胞过滤降低，而在退行性疾病患者中仅为6.6%。血液黏度数据显示病理状况与血液流变学改变之间的联系较少。提示血液流变学改变可能有助于某些慢性脑病临床类型的发病机制。因此建议将血液流变学检测纳入此类患者的诊断程序中，并且也可用于确定适当的治疗方法。
