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[尿毒症引起的血液流变学变化。血液透析的影响]

[Hemorheological changes induced by uremia. Effects of hemodialysis].

作者信息

Delsignore R, David S, Francia M T, Bottazzi G, Crotti G

出版信息

Ric Clin Lab. 1985;15 Suppl 1:335-45.

PMID:4035225
Abstract

Fifteen patients affected by chronic uremia and treated with hemodialysis were studied. The main hemorheological parameters were evaluated in basal conditions and after hemodialytic therapy and were correlated with some hematochemical indices. Although some limitations to the purpose of this study derive from the heparinization of the blood during hemodialysis, the results of this study demonstrate that erythrocyte filtration does not significantly change during the hemodialytic therapy. The only hemorheological parameter altered in the uremic patient is represented by plasma viscosity; this is probably due to the increase of fibrinogenemia in these patients.

摘要

对15例接受血液透析治疗的慢性尿毒症患者进行了研究。在基础状态和血液透析治疗后评估了主要血液流变学参数,并将其与一些血液化学指标进行了关联。尽管本研究目的存在一些局限性,源于血液透析期间血液的肝素化,但本研究结果表明,血液透析治疗期间红细胞滤过率无明显变化。尿毒症患者唯一改变的血液流变学参数是血浆粘度;这可能是由于这些患者纤维蛋白原血症增加所致。

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