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Editorial: Organ preservation for rectal cancer patients.社论：直肠癌患者的器官保存
Front Surg. 2025 Apr 25;12:1600115. doi: 10.3389/fsurg.2025.1600115. eCollection 2025.
2
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Dis Colon Rectum. 2024 Mar 1;67(3):369-376. doi: 10.1097/DCR.0000000000003096. Epub 2023 Nov 20.
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6
Cost-Effectiveness of Total Neoadjuvant Therapy With Selective Nonoperative Management for Locally Advanced Rectal Cancer: Analysis of Data From the Organ Preservation for Rectal Adenocarcinoma Trial.局部晚期直肠癌全新辅助治疗联合选择性非手术治疗的成本效益：来自直肠腺癌器官保留试验的数据分析
J Clin Oncol. 2025 Feb 20;43(6):672-681. doi: 10.1200/JCO.24.00681. Epub 2024 Oct 31.
7
[Total neoadjuvant therapy followed by watch and wait approach or organ preservation for MRI stratified low-risk rectal cancer: early result from a prospective, single arm trial].[新辅助综合治疗后观察等待或对MRI分层低风险直肠癌行器官保留：一项前瞻性单臂试验的早期结果]
Zhonghua Wei Chang Wai Ke Za Zhi. 2020 Mar 25;23(3):258-265. doi: 10.3760/cma.j.cn.441530-20200222-00070.
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[Outcome of watch and wait strategy or organ preservation for rectal cancer following neoadjuvant chemoradiotherapy: report of 35 cases from a single cancer center].[新辅助放化疗后直肠癌的观察等待策略或器官保留结果：来自单一癌症中心的35例报告]
Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Apr 25;20(4):417-424.
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Predictive Value of Magnetic Resonance Complete Response After Neoadjuvant Therapy for Rectal Cancer.新辅助治疗后直肠癌磁共振完全缓解的预测价值
J Surg Res. 2025 Feb;306:474-478. doi: 10.1016/j.jss.2024.12.042. Epub 2025 Jan 27.
10
Organ preservation strategy: new therapeutic alternative in rectal cancer.器官保存策略：直肠癌的新治疗选择。
J Egypt Natl Canc Inst. 2023 Apr 24;35(1):10. doi: 10.1186/s43046-023-00169-0.

本文引用的文献

1
Beyond survival: a comprehensive review of quality of life in rectal cancer patients.超越生存：直肠癌患者生活质量的全面综述
Ann Coloproctol. 2024 Dec;40(6):527-537. doi: 10.3393/ac.2024.00745.0106. Epub 2024 Dec 20.
2
Nonoperative management of rectal cancer.直肠癌的非手术治疗
Front Oncol. 2024 Dec 6;14:1477510. doi: 10.3389/fonc.2024.1477510. eCollection 2024.
3
Non-operative management of rectal cancer: Highlighting the controversies.直肠癌的非手术治疗：突出争议点
World J Gastrointest Surg. 2024 Jun 27;16(6):1501-1506. doi: 10.4240/wjgs.v16.i6.1501.
4
Comparison of outcomes of abdominoperineal resection vs low anterior resection in very-low rectal cancer.超低位直肠癌行腹会阴联合切除术与低位前切除术的疗效比较。
J Gastrointest Surg. 2024 Sep;28(9):1450-1455. doi: 10.1016/j.gassur.2024.06.008. Epub 2024 Jun 17.
5
Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database (IWWD).直肠癌新辅助治疗后观察等待：国际观察等待数据库（IWWD）中首次重新评估时完全缓解与无完全缓解患者结局的比较。
Br J Surg. 2023 May 16;110(6):676-684. doi: 10.1093/bjs/znad051.
6
PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer.PD-1 阻断在错配修复缺陷、局部晚期直肠癌中的应用。
N Engl J Med. 2022 Jun 23;386(25):2363-2376. doi: 10.1056/NEJMoa2201445. Epub 2022 Jun 5.
7
Lateral lymph node dissection in rectal cancer: State of the art review.直肠癌侧方淋巴结清扫：现状综述
Eur J Surg Oncol. 2022 Nov;48(11):2315-2322. doi: 10.1016/j.ejso.2021.11.003. Epub 2021 Nov 8.
8
Neoadjuvant PD-1 blockade with toripalimab, with or without celecoxib, in mismatch repair-deficient or microsatellite instability-high, locally advanced, colorectal cancer (PICC): a single-centre, parallel-group, non-comparative, randomised, phase 2 trial.托瑞帕利单抗新辅助PD-1阻断联合或不联合塞来昔布治疗错配修复缺陷或微卫星高度不稳定的局部晚期结直肠癌（PICC）：一项单中心、平行组、非对照、随机、2期试验
Lancet Gastroenterol Hepatol. 2022 Jan;7(1):38-48. doi: 10.1016/S2468-1253(21)00348-4. Epub 2021 Oct 22.
9
Watch and wait approach in rectal cancer: Current controversies and future directions.直肠癌的观察与等待策略：当前的争议与未来方向。
World J Gastroenterol. 2020 Aug 7;26(29):4218-4239. doi: 10.3748/wjg.v26.i29.4218.
10
A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta-analysis.新辅助放化疗后临床完全缓解的局部进展期直肠癌采用观察等待策略：系统评价和荟萃分析。
Lancet Gastroenterol Hepatol. 2017 Jul;2(7):501-513. doi: 10.1016/S2468-1253(17)30074-2. Epub 2017 May 4.

Editorial: Organ preservation for rectal cancer patients.

作者信息

Negoi Ionut, Monson John R T, Bustamante-Lopez Leonardo, Garoufalia Zoe, D'Andrea Vito, Emile Sameh Hany

机构信息

Department of General Surgery, Clinical Emergency Hospital of Bucharest, Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania.

Department of Colorectal Surgery, Northshore University Hospital, Northwell Health, New York, NY, United States.

出版信息

Front Surg. 2025 Apr 25;12:1600115. doi: 10.3389/fsurg.2025.1600115. eCollection 2025.

DOI:10.3389/fsurg.2025.1600115
PMID:40352304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12061697/
Abstract
摘要