Golvari Pooria, Morales Tyrone, Rahmani Azina, Kuebler Stephen M, Touma Jimmy
Department of Chemistry, University of Central Florida, Orlando, Florida 32816, United States.
CREOL, The College of Optics and Photonics, University of Central Florida, Orlando, Florida 32816, United States.
ACS Omega. 2025 Apr 22;10(17):17783-17793. doi: 10.1021/acsomega.5c00293. eCollection 2025 May 6.
A method is reported for depositing gold nanoparticles (AuNPs) rapidly and uniformly onto centimeter-scale substrates. AuNPs functionalized with a low-density coating of poly(ethylene glycol) (PEG) are first dispersed into dichloromethane (DCM) containing cetyltrimethylammonium chloride (CTAC) then deposited onto hydroxyl terminated surfaces using centrifugal force. The degree of clustering on the surface is found to be controllable by varying the concentration of CTAC. The sparse coating of PEG stabilizes the AuNPs in DCM at sub-μM concentrations of CTAC, enabling deposition of AuNPs as a nonagglomerated submonolayer. Hence, the method can be used for rapid, scalable, and uniform deposition of isolated AuNPs as well as clustered agglomerates with tunable morphology and optical response. The approach is extended for depositing citrate- and PEG-capped AuNPs into the nanowells of topographically patterned substrates. Centrifugal deposition is first used to deposit AuNPs onto the patterned substrate. Wiping with a tissue selectively removes AuNPs from the top surface. This yields AuNPs deposited uniformly into nanowells of the substrate. The overall approach may be useful for large-scale selective deposition of AuNPs onto patterned surfaces that are attractive for SERS and sensors.
报道了一种将金纳米颗粒（AuNPs）快速且均匀地沉积到厘米级基底上的方法。首先将用低密度聚乙二醇（PEG）涂层功能化的AuNPs分散到含有十六烷基三甲基氯化铵（CTAC）的二氯甲烷（DCM）中，然后利用离心力将其沉积到羟基封端的表面上。发现通过改变CTAC的浓度可以控制表面上的聚集程度。PEG的稀疏涂层在亚微摩尔浓度的CTAC下使AuNPs在DCM中稳定，从而能够以非团聚的亚单层形式沉积AuNPs。因此，该方法可用于快速、可扩展且均匀地沉积孤立的AuNPs以及具有可调形态和光学响应的聚集团聚体。该方法被扩展用于将柠檬酸盐和PEG封端的AuNPs沉积到具有形貌图案的基底的纳米孔中。首先使用离心沉积将AuNPs沉积到图案化的基底上。用纸巾擦拭可选择性地从顶面去除AuNPs。这使得AuNPs均匀地沉积到基底的纳米孔中。总体方法可能有助于将AuNPs大规模选择性沉积到对表面增强拉曼光谱（SERS）和传感器有吸引力的图案化表面上。
