Yang Ping, Wang Li, He Yang
Department of Oncology, Shanghai Eighth People's Hospital, Shanghai, China.
Department of Urology, Liyang People's Hospital, Liyang, Jiangsu, China.
Medicine (Baltimore). 2025 May 9;104(19):e42388. doi: 10.1097/MD.0000000000042388.
Primary prostate sarcomas are highly malignant tumors characterized by their low incidence and poor prognosis. Due to this rarity, we present a limited number of case series.
In this report, we detail the clinical diagnosis, treatment, and prognosis of the last 6 primary prostatic sarcoma cases.
The 6 patients, all adults aged between 21 and 51 years, were diagnosed pathologically through needle biopsy or surgical specimens.
All patients underwent chemotherapy.
At the time of the last follow-up, only 1 patient continued treatment, while the other 5 had succumbed to disease progression. The overall survival time ranged from 3 to 46 months.
Primary prostatic sarcoma presents with an insidious onset and rapid progression, lacking standard treatment options and associated with a very poor prognosis. Early detection and timely surgical intervention may improve the cure rate and extend survival time for affected patients.
原发性前列腺肉瘤是高度恶性肿瘤，其特点是发病率低且预后差。由于这种罕见性，我们展示了数量有限的病例系列。
在本报告中，我们详细介绍了最近6例原发性前列腺肉瘤病例的临床诊断、治疗和预后。
这6例患者均为年龄在21至51岁之间的成年人，通过穿刺活检或手术标本进行病理诊断。
所有患者均接受了化疗。
在最后一次随访时，只有1例患者继续接受治疗，而其他5例患者因疾病进展死亡。总生存时间为3至46个月。
原发性前列腺肉瘤起病隐匿且进展迅速，缺乏标准治疗方案，预后极差。早期发现并及时进行手术干预可能提高治愈率并延长患者的生存时间。
