Li Zusheng, Liu Haibin, Li Mengzhen, Liu Shuhan, Pan Xin, Zhao Hongling, Xue Chundong, Xu Dong
Department of Neurology, Central Hospital of Dalian University of Technology, Dalian, Liaoning, China.
School of Sport and Health Sciences, Dalian University of Technology, Dalian, Liaoning, China.
Physiol Rep. 2025 May;13(9):e70361. doi: 10.14814/phy2.70361.
Exercise intensity has been shown to elicit different cerebral blood flow velocity (CBFv) responses. This study aimed to compare the acute effects of resistance exercise at different intensities on hemodynamics and cerebrovascular reactivity in healthy young males. Eleven healthy young males were recruited, and three trials of dumbbell alternating curls were performed in order of increasing intensity: low (30%-35% 1RM), medium (55%-60% 1RM), and high (75%-80% 1RM). Blood pressure, heart rate, CBFv, and cerebrovascular reactivity were measured at baseline, 1, 5, and 10 min after exercise. (1) At 10 min, the mean blood pressure in the medium-intensity was significantly lower than that at baseline. (2) At 1 min, the systolic velocity of the middle cerebral artery in the medium-intensity increased significantly. (3) At 1 min, the pulsatility index (PI) and resistance index (RI) of the high-intensity increased significantly. At 10 min, the PI and RI of the medium-intensity were significantly lower than the baseline. (4) At 5 min, the breath-holding index significantly increased in the medium-intensity but decreased in the high-intensity. Compared with low and high intensities, medium-intensity resistance exercise may be more effective in lowering blood pressure and enhancing cerebral hemodynamics.
运动强度已被证明会引发不同的脑血流速度（CBFv）反应。本研究旨在比较不同强度的抗阻运动对健康年轻男性血液动力学和脑血管反应性的急性影响。招募了11名健康年轻男性，并按照强度递增的顺序进行了三次哑铃交替弯举试验：低强度（30%-35% 1RM）、中等强度（55%-60% 1RM）和高强度（75%-80% 1RM）。在运动前基线、运动后1、5和10分钟测量血压、心率、CBFv和脑血管反应性。（1） 在10分钟时，中等强度组的平均血压显著低于基线水平。（2） 在1分钟时，中等强度组大脑中动脉的收缩期速度显著增加。（3） 在1分钟时，高强度组的搏动指数（PI）和阻力指数（RI）显著增加。在10分钟时，中等强度组的PI和RI显著低于基线水平。（4） 在5分钟时，中等强度组的屏气指数显著增加，而高强度组则下降。与低强度和高强度相比，中等强度的抗阻运动在降低血压和增强脑血液动力学方面可能更有效。
