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氧化青藤碱在治疗人类疾病医学中的生物学潜力:药理活性及相关分子机制的最新进展

Biological Potential of Oxoglaucine in Medicine for the Treatment of Human Disorders: An Update on Pharmacological Activities and Related Molecular Mechanism.

作者信息

Patel Kanika, Patel Dinesh Kumar

机构信息

Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, Uttar Pradesh, India.

出版信息

Recent Adv Antiinfect Drug Discov. 2025;20(2):77-91. doi: 10.2174/0127724344297762240815073618.

DOI:10.2174/0127724344297762240815073618
PMID:40356388
Abstract

Medicinal plants are an integral part of the medical system in many countries around the world. Natural products have been used as important biological sources for drug discovery over the past half-century. Alkaloids are a group of natural compounds that contain a basic nitrogen atom. Oxoglaucine is a phytochemical of the oxoaporphines class phytochemical isolated from Maxim, , and . The purpose of this study is to analyze all the scientific information about oxoglaucine in order to know the health-beneficial potential of oxoglaucine in medicine. The detailed pharmacological activities of oxoglaucine are analyzed and discussed in this review. The scientific data of the present review about oxoglaucine were collected from PubMed, Scopus, Science Direct, and Google using the terms oxoglaucine, oxoaporphines, alkaloid, phytochemical, pharmacological, and herbal medicine. The scientific findings of the present review article describe the biological importance and therapeutic effectiveness of oxoglaucine in medicine. The present article scientific data signified the biological potential of oxoglaucine against inflammatory diseases, arthritis, osteoarthritis, immune response, enterovirus, and poliovirus. Furthermore, its anticancer, antiaggregation, antifungal, antiprotozoal, and cytotoxic potential are also described in this review article. The scientific information in this article will be helpful to all the scientific peoples of biological science to understand the therapeutic potential of oxoglaucine in medicine.

摘要

药用植物是世界上许多国家医疗体系中不可或缺的一部分。在过去的半个世纪里,天然产物一直是药物发现的重要生物来源。生物碱是一类含有碱性氮原子的天然化合物。氧化青藤碱是从[植物名称未完整给出]中分离出的氧阿朴啡类植物化学物质。本研究的目的是分析所有关于氧化青藤碱的科学信息,以便了解其在医学上的健康有益潜力。本文对氧化青藤碱的详细药理活性进行了分析和讨论。本综述中关于氧化青藤碱的科学数据是从PubMed、Scopus、Science Direct和谷歌收集的,使用的关键词有氧化青藤碱、氧阿朴啡、生物碱、植物化学物质、药理学和草药。本综述文章的科学发现描述了氧化青藤碱在医学上的生物学重要性和治疗效果。本文的科学数据表明氧化青藤碱对炎症性疾病、关节炎、骨关节炎、免疫反应、肠道病毒和脊髓灰质炎病毒具有生物学潜力。此外,本综述文章还描述了其抗癌、抗聚集、抗真菌、抗原虫和细胞毒性潜力。本文中的科学信息将有助于所有生物科学领域的科研人员了解氧化青藤碱在医学上的治疗潜力。

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本文引用的文献

1
Cellulose nanocrystals from celery stalk as quercetin scaffolds: A novel perspective of human holo-transferrin adsorption and digestion behaviours.芹菜茎源纤维素纳米晶体作为槲皮素支架:人血转铁蛋白吸附和消化行为的新视角。
Luminescence. 2024 Jan;39(1):e4634. doi: 10.1002/bio.4634.
2
Oxoaporphine Pr(III) complex inhibits hepatocellular carcinoma progression and metastasis by disrupting tumor cell-macrophage crosstalk.氧代阿朴啡钬(III)配合物通过破坏肿瘤细胞-巨噬细胞串扰抑制肝癌进展和转移。
Biomed Pharmacother. 2023 Dec 31;169:115849. doi: 10.1016/j.biopha.2023.115849. Epub 2023 Nov 15.
3
Bracteatinine and isogroenlandicine, two new isoquinoline alkaloids isolated from Corydalis bracteata and their effect on platelet function.
来自紫堇属植物苞叶延胡索的两个新异喹啉生物碱——苞叶延胡索宁碱和异格劳德宁碱及其对血小板功能的影响。
Fitoterapia. 2023 Dec;171:105697. doi: 10.1016/j.fitote.2023.105697. Epub 2023 Oct 4.
4
Bioprospecting-based untargeted metabolomics identifies alkaloids as potential anti-inflammatory bioactive markers of Ocotea species (Lauraceae).基于生物勘探的非靶向代谢组学鉴定出生物碱类化合物,其可能是拉拉藤科(Lauraceae)植物奥克泰欧属(Ocotea)的潜在抗炎生物活性标志物。
Phytomedicine. 2023 Nov;120:155060. doi: 10.1016/j.phymed.2023.155060. Epub 2023 Sep 3.
5
UPLC-ESI-QTOF-MS assisted targeted metabolomics to study the enrichment of vinca alkaloids and related metabolites in Catharanthus roseus plants grown under controlled LED environment.UPLC-ESI-QTOF-MS 辅助靶向代谢组学研究在受控 LED 环境下生长的长春花植物中长春碱类生物碱及相关代谢物的富集。
J Pharm Biomed Anal. 2023 Oct 25;235:115611. doi: 10.1016/j.jpba.2023.115611. Epub 2023 Jul 29.
6
Oxoglaucine Suppresses Hepatic Fibrosis by Inhibiting TGFβ-Induced Smad2 Phosphorylation and ROS Generation.白杨素通过抑制 TGFβ诱导的 Smad2 磷酸化和 ROS 生成抑制肝纤维化。
Molecules. 2023 Jun 24;28(13):4971. doi: 10.3390/molecules28134971.
7
Supercritical fluid chromatography based on reversed-phase/ ion chromatography mixed-mode stationary phase for separation of spirooxindole alkaloids.基于反相/离子色谱混合模式固定相的超临界流体色谱法分离螺环吲哚生物碱。
J Chromatogr A. 2023 Aug 30;1705:464163. doi: 10.1016/j.chroma.2023.464163. Epub 2023 Jun 16.
8
Hunteriasines A - D, tryptamine-derived alkaloids from Hunteria umbellata.亨特雅星 A-D,一种来源于伞序鹅掌柴的色胺衍生生物碱。
Phytochemistry. 2023 Sep;213:113752. doi: 10.1016/j.phytochem.2023.113752. Epub 2023 Jun 15.
9
Rapid determination of five common toxic alkaloids in blood by UPLC-MRM-IDA-EPI: Application to poisoning case.超高效液相色谱-串联质谱-信息依赖性采集-增强子离子扫描法快速测定血液中五种常见有毒生物碱:中毒案例应用。
Leg Med (Tokyo). 2023 Jul;63:102267. doi: 10.1016/j.legalmed.2023.102267. Epub 2023 May 2.
10
Aporphines: A privileged scaffold in CNS drug discovery.阿朴啡类生物碱:中枢神经系统药物发现中的优势骨架。
Eur J Med Chem. 2023 Aug 5;256:115414. doi: 10.1016/j.ejmech.2023.115414. Epub 2023 May 6.